Change in White Male Rats’ Weight and Epididimic Histology Due to the Provision of White Turmeric Extract and Fraction

  • Rinda Lamdayani STIKES Abdurahman Palembang
  • Aryanti Aryanti STIKES Abdurahman Palembang
Keywords: extract, fraction, thickness of caput epithelium, thickness of cauda epithelium, thickness of corpus epithelium, weight of epididymis


The low participation of Men in the family planning program is due to the limited choice of male contraceptives that can be used. This makes experts trying to find a way that is safe for men, one way is to switch plants that can inhibit the spermatogenesis. One of the traditional medicines that has been studied and has anti-fertility effectiveness is the white turmeric plant. This study aimed to determine the effect of extracts and fraction of white turmeric on changes in weight and histology of white male rats (Rattus norvegicus) epididymis. This research was an experimental study using a completely randomized design (CRD). The samples in this study were 25 white male rats that met the inclusion criteria which were divided into 5 groups, each group consisting of 5 rats obtaining a dose of 300 mg/kgBW/day, treated for 48 days and stopped for surgery on the day 49. After that, the analysis was carried out using One Way Anova test and continued with Duncan's test. The provisions of extracts and fractions of white turmeric can reduce the weight and histological structure of the epididymis of the head, corpus, and cauda.


Arsyad, KM 1980. Prociding Spermatogenesis Seminar. Board of the Andrology Association (PANDI) Surabaya.

Ashdown, RR and ESE Hafez. 1993. Anatomy of Male Reproduction. Itz ESE Hafez (ed): Reproduction in Farm Animals. 6 "ed. Lea & Febiger. Philadelphia.pp: 3-19.

Ashok, P., B. Meenakshi. 2004. Contraceptive Effect Of Curcuma longa (L.) in Male Albino Rat. Available at:http: // www. Asian J Opened: 23.10.2015

Ashfahani, ED, Wiratmini, NI Sukmaningsih. 2000. Motility and Viability of Mouse Spermatozoa (Musmusculus L.) After Giving White turmeric Extract (Curcuma Zedoaria (Berg.) Roscoe.). Journal of Biology XIV. ISSN 1410 5292.

Biology, J., & Viability, ON (2010). Motility and Viability of Mice (Mus Musculus L.) Spermatozoa After Giving White turmeric Extract (Curcuma Zedoaria (Berg.) Roscoe.). Journal of Biology, 14 (1).

Cholifah, S., Arsyad, & Salni. (2014). The Effect of Giving Pare Extract (Momordica Charantia, L) on the Histological Structure of the Testes and Epididymis of Male Rats. Mks, 46 (2), 149–157.

Delfita, R. (2014). Antifertility Potential of Black Tea Extract in Male Mice (Mus musculus L.). Journal of Science and Technology of IAIN Batusangkar, 6 (2), 181–188.

Handajani, NS (2003). Cytostatic activity of White turmeric (Curcuma zedoaria (Berg.) Roscoe.) On the spermatogenic cells of Mice (Mus Musculus L.) BioSMART Journal 5 (2): 120-123.

Hanum M, (2010). Reproductive Biology, Nuhamedika, Jogjakarta

Hartono Maiyani, Nurlaila, Batubara Irmanida (2011) Potential of White turmeric (Curcuma Zedoaria) as Anti-Bacterial and Chemical Compound Contents. Bogor Agricultural Institute 203-212

Martinez GM, Chandra A, Amba JC, Jones J, Mosher WD. Fertility, contraception, and fatherhood data on men and women from cycle 6 (2002) of the 2002 National Survey of Family Growth. Vital Health and Statistics; 2006: 2003: 1

Mitayani. (2009). The Effect of Pare (Momordica charantia L) Extract on the Number of Spermatozoa, Seminiferous Tubule Diameter and Testicular Weight of Wistar Male Rats as Natural Contraceptives. Unpad Thesis.

Naomi, B., & Sari, R. (2016). Email: 1 (1), 44–59.

Siswanti, T., Astirin, OP, & Widiyani, T. (2003). Effect of White turmeric Extract (Curcuma zedoaria Rosc.) On Spermatogenesis and Quality of Mice (Mus musculus L.) Spermatozoa. 5 (April), 38–42.

Wahyuni, S., Agungpriyono, S., Agil, M., & Yusuf, LT (2012). Histology and Histomorphometry of Testes and Peak Epididymis (Muntiacus muntjak muntjak) in Hard Antler Period. Veterinary, 13 (3), 211–219.

How to Cite
Lamdayani, R., & Aryanti, A. (2021). Change in White Male Rats’ Weight and Epididimic Histology Due to the Provision of White Turmeric Extract and Fraction. Indonesian Journal of Global Health Research, 3(1), 15-28.