Indonesian Journal of Global Health Research

The Effect of Combined Music Therapy and Stress Ball on Pain During Vascular Access Cannulation in Hemodialysis Patients

2025-04-27T12:30:01+00:00

Hemodialysis remains the main therapy for patients with kidney failure. During the cannulation process, which is the insertion of a needle into a vascular access, hemodialysis patients often experience pain. The combination of music therapy and the use of stress balls is an example of a non-pharmacological intervention that can be used to overcome pain during cannulation. Objective to identify the effectiveness of the combination of music therapy and stress balls on pain in hemodialysis patients during the vascular access cannulation process. This study used a phased cross-over design, where each respondent received both treatments alternately. A total of 42 respondents were divided into two groups: the experimental group (n = 21) received music therapy and stress balls , while the control group (n = 21) received standard hospital therapy, namely deep breathing relaxation. Furthermore, the two groups exchanged treatments. The level of pain was measured using a VAS (Visual Analog Scale). The results showed that the combination of music therapy and stress balls was effective in reducing pain during the cannulation process, with significant changes in pain levels after insertion (p < 0.001). Cohen's d effect size of -0.632 indicates that combination therapy has a stronger effect in reducing pain than deep breathing relaxation therapy.

Effectiveness of Agent Disinfectant Prior to Intravenous Catheter Placement on Infection and Potential Adverse Effects Among Neonates: A Systematic Review

2025-04-27T13:24:51+00:00

Several disinfection agents have been proven to have controversial issues with neonates. These agents continue to be used to disinfect prior to the insertion of intravenous catheters, both peripheral and central venous catheters in neonatal care rooms. Objective to identify the effectiveness of disinfection agents used prior to intravenous catheter placement among neonates and the possible adverse events. A systematic review was conducted. Databases including Pubmed, Science Direct, Proquest, Ebscohost, Clinical Key Nursing, and Wiley were searched from inception to October 2024. The eligibility criteria were neonates who needed intravenous catheter placement (peripheral or central), with experimental research design, and articles written in English. The quality of studies was assessed depending on the study design. Our study is registered on PROSPERO number CRD42024618924. 1119 articles were found. After the screening processes, we finally included 7 articles. Disinfection agents frequently used in neonatal settings in the included studies were chlorhexidine (with varying concentrations), aqueous and alcohol-based, and povidone-iodine 10%. The disinfectant used prior to the insertion of the intravenous catheter was effective in reducing pathogen colonization on the skin and preventing bloodstream infection. Even so, there were some concerns regarding the adverse effects of the disinfectant agent used. The disinfection prior to invasive procedures in neonatal care is a debated topic. Despite this, inadequate disinfection poses more life-threatening due to the risk of bloodstream infection. Key factors to consider when choosing an appropriate topical agent disinfectant prior to intravenous catheter placement in neonates include gestational age, birth weight, and skin condition.

Factors Associated with Frailty Syndrome in the Elderly: A Systematic Review

2025-04-27T13:43:05+00:00

Frailty syndrome is a common condition among the elderly. Frailty has become a major health issue in the 21st century, affecting older adults and being associated with various negative outcomes such as decreased quality of life, increased mortality, hospital admissions, risk of falls, depression, and dementia. Objective: This study aims to identify and summarize the factors associated with frailty syndrome in the elderly through a systematic literature review. The findings are expected to serve as a basis for early prevention and management efforts of frailty in older adults. This study employs a systematic literature review method by analyzing 7 relevant journal articles published between 2020 and 2025. Articles were sourced from databases such as ProQuest, SpringerLink, and ClinicalKey for Nursing, selected based on topic relevance and publication quality to provide a comprehensive overview of the factors influencing frailty syndrome in the elderly. Based on the review of 7 journal articles, several factors influencing frailty syndrome were identified, including: age over 80 years, polypharmacy (use of multiple medications), gender, low body mass index (BMI), history of hospitalization, previous alcohol use, history of falls, living alone, presence of comorbidities, and impaired cognitive function. Frailty syndrome in the elderly is influenced by various risk factors spanning physical, psychological, and social aspects. Identifying these factors is crucial to support early interventions and preventive efforts, thereby improving the quality of life of older adults and reducing the risk of further complications. This systematic review can serve as a reference in developing strategies for the prevention and management of frailty among the elderly population.

Potential of Bioactive Compounds from Gambier (Uncaria Gambir Roxb.) in Modulating Cognitive Function: A Scoping Review

2025-04-27T21:23:25+00:00

Aging is a process of diminishing tissue capacity for self-repair and maintenance of normal structure and function, leading to vulnerability to injury and damage. The high incidence of neurodegenerative diseases coincides with increased life expectancy in the elderly. An unavoidable negative effect of neurodegenerative diseases is the potential to cause cognitive decline. Gambier (Uncaria gambir Roxb.), containing 90% catechin, is a traditional plant with potential to enhance cognitive function. This scoping review aims to map existing research on the potential of bioactive compounds from gambier in modulating cognitive function, based on research articles in journals from the last 10 years in the PubMed, PMC, Google Scholar, and Google Scholar databases (2014-2024). The research was conducted by collecting research data from the last 10 years, totaling 12 articles. Among these, 4 articles met the inclusion criteria, focusing on the potential of bioactive compounds from gambier in modulating cognitive function. The article screening was conducted systematically using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) as 1 a guideline, followed by screening based on inclusion and exclusion criteria. This scoping review found potential for bioactive compounds from gambier in modulating cognitive function, as evidenced by increased Montreal Cognitive Assessment (MoCA) scores, decreased levels of Beta Amyloid (Aβ), Microtubule-Associated Protein Tau (MAPT), Malondialdehyde (MDA) levels, and increased Brain-Derived Neurotrophic Factor (BDNF). The potential of catechin, the primary bioactive compound in gambier, which possesses antioxidant, anti-inflammatory, and neuroprotective effects, yields beneficial results in enhancing cognitive function in the elderly.