Hilirisasi Produk Krenova Krim Galenik untuk Perawatan Luka bagi Praktisi Kesehatan
Abstract
Penerapan hasil riset civitas akademika Universitas Kusuma Husada Surakarta terkait eksplorasi potensi bahan alam dan pengembangan teknologi formulasi sediaan farmasi berbasis bahan galenik bioimunostimulator perlu dioptimalkan untuk menunjang efektivitas terapi perawatan luka kronis. Tujuan kegiatan sesuai paradigma kegiatan pengabdian pada masyarakat melalui fasilitasi Program Inovokasi Universitas Kusuma Husada Surakarta tahun 2024 adalah diseminasi dan implementasi sediaan galenik sebagai produk krenova berbasis knowledge based economy yang siap dihilirisasi dan dikomersialisasi secara profesional; mandiri serta berkelanjutan. Metode kegiatan meliputi transfer knowledge workshop manajemen perawatan luka manajement perawatan luka kepada 30 orang praktisi atau perawat mandiri dan webinar kolaborasi internasional antara Universitas Kusuma Husada Surakarta dan Instituto Ciencias Da Saude (ICS) Timor Leste tentang kuliah pakar manajemen perawatan luka antara yang diikuti oleh 325 peserta aktif secara online. Diseminasi dan implementasi produk krenova civitas akademika UKH Surakarta sediaan galenik seromukoid bekicot, ekstrak kulit durian dan atau kitosan sebagai healthy and safety product untuk wound healing melalui kolaborasi link and match antara UKH Surakarta dengan mitra industry herbal, bidang layanan kesehatan yaitu praktisi mandiri, home care, ataupun unit layanan kesehatan lain guna mendukung tercapainya hilirisasi produk krenova krim galenik antiinflamasi dan mendukung suksesnya program Pemerintah dalam penanggulangan perawatan luka kronis di Indonesia.
References
Agustin, W.R., Harti, A.S., Crisdian S, H.A, Saputro, S.D., Saelan, S. (2023). The Effectiveness of Galenic Cream of Durian Peel Extract and Chitosan for Treatment of Diabetic Ulcers. Indonesian Nursing Journal of Education and Clinic (INJEC) .8(2),262–272.https://injec.aipni-ainec.org/index.php/INJEC/ article/view/597
Anggriani, S., Hariani, & Ulfa, D. (2019). Efektifitas Perawatan Luka Modern Dressing dengan Metode Moist Wound Healing pada Ulkus Diabetik di Klinik Perawatan Luka ETN Centre Makassar. Artikel Koleksi Politeknik Kesehatan Makassar, 10, 2087–122.
Han, George dan Roger Ceilley. (2017). Chronic Wound Healing: A Review of Current Management and Treatments. Advance in Therapy, 34(3), 599–610.
Handayani, L.T. (2016). Studi Meta Analisis Perawatan Luka Kaki Diabetes dengan Modern Dressing. The Indonesian Journal of Health Science, 6(2). https://doi.org/https: //doi.org/10.32528/the.v6i2.133.
Harti, A.S., Sulisetyawati, S.D., Murharyati, A., Oktariani, M., & Wijayanti, I.B. (2016). The effectiveness of snail slime and chitosan in wound healing. International Journal of Pharma Medicine and Biological Science, 5(1),76-80. doi: 10.18178/ijpmbs.5.1.76-80.
Harti, A.S., Estuningsih, Heni N.K., Siswiyanti, Arum S., (2016). In vitro Synergistic Effect of Snail Slime and Chitosan against Staphylococcus aureus. International Journal of Pharma Medicine and Biological Science . 5 (2 & 3),137-141
Harti, A.S., Nony P. Rahajeng P., 2019. Antimicrobial Bioactive Compounds of Snail Seromucoid as Biological Response Modifier Immunostimulator. Journal Microbiology Indonesia, 13 (2) DOI 10.5454/mi.13.2.3.
Harti, A.S., Rahajeng P., Nony P., Yusup S.S (2020). The Effectiveness of Snail Seromucous and Chitosan as Biological Response Modifiers Immunostimulatory on Lymphocyte Proliferation. Proceeding ICComSET 2020. The 3rd International Conference on Computer, Science, Engineering and Technology Universitas Muhammadiyah Tasikmalaya. http://www.3rdiccomset.umtas.ac.id
Harti, A.S., Yusup S.S, Rahajeng P., Tresia U., Erlina W., Mellia S.I., (2021). The Effectiveness of Chitosan and Snail Seromucous as Anti Tuberculosis Drugs. Open Access Macedonian Journal of Medical Sciences. 9(A):510-514. https://doi.org/ 10.3889/oamjms.2021.6466.
Harti, A. S., Sutanto, Y. S., Agustin, W. R., Putriningrum, R., Irdianty, M. S., Saelan, S., & Ardiani,N.D.(2024). The Effectiveness of Anti-Inflammatory Cream Galenic Preparations Based on Snail Seromucoid, Durian Peel Extract Polysaccharides and Chitosan in the Wound Healing Process (In Vivo). International Journal of Public Health Excellence (IJPHE), 3(2), 729–740
Hasem, N.H., Fuzi, S.F.Z.M., Kormin, F., Bakar, M.F.A., & Sabran, S.F. (2018). Extraction and partial characterization of durian rind pectin. IOP Conf. Series: Earth and Environmental Science 269. IOP Publishing International Conference on Biodiversity, 11–3. doi:0.1088/755-315/269/1/012019.
Khoo, H.E, Azlan, A., Kong, K.W.,& Ismail, A. (2016). Phytochemicals and Medicinal Properties of Indigenous Tropical Fruits with Potential for Commercial Development. Evidence-Based Complementary and Alternative Medicine. Article ID 7591951 https://doi.org/10.1155/2016/.
Kumoro, A.C., Alhanif, M., & Wardhani, D.H. (2020). A Critical Review on Tropical Fruits Seeds as Prospective Sources of Nutritional and Bioactive Compounds for Functional Foods Development: A Case of Indonesian Exotic Fruits. Int J Food Sci. doi:10.1155/2020/4051475.
Marchianti, A.C.N. (2019). Gel Formulations Of Merremia Mammosa (Lour.) Accelerated Wound Healing Of The Wound In Diabetic Rats. Journal of Traditional and Complementary Medicine. DOI: 10.1016/j.jtcme.2019.12.002.
Ma’rufah et. al., 2022. Pelatihan Kader Posyandu Dan Posbindu Untuk Meningkatkan Performa Kader Puskesmas Gondangrejo Kabupaten Karanganyar. Smart Society Empowerment Journal. 2 (1) 25 - 29
Nugroho, A., Adianto, C., & Patria, Y. (2020). Nano-Androcerum Nano-Androcerum: Inovasi Wound Healing Gel Dari Nanopartikel Daun Binahong dan Kayu Manis Sebagai Akselerator Regenerasi Sel Pada Luka Kronis. Berkala Ilmiah Mahasiswa Farmasi Indonesia (BIMFI), 7(1), 026-042. https://doi.org/10.48177/bimfi.v7i1.11
Pereira, Ruben F. & Paulo J. Bartolo. (2016). Traditional Therapies for Skin Wound Healing. Advances in Wound Care, 5(5), 208-229.
Purnama, H., Sriwidodo, Ratnawulan, S. (2020). Review Sistematik: Proses Penyembuhan Dan Perawatan. Farmaka Suplemen, 15(2), 251 – 257.
Sugiharta, S. dan Widia Ningsih (2021). Evaluasi Stabilitas Sifat Fisika Kimia Sediaan Krim Ketoconazole dengan Metode Stabilitas Penyimpanan Jangka Panjang. Majalah Farmasetika, 6 (Suppl1) 162-175. https://doi.org/10.24198/mfarmasetika. v6i0
Sutanto YS, Sutanto M, Harti AS, Puspawati N.(2020). The sensitivity test of Mycobacterium tuberculosis isolates from suspect tuberculosis patients to the seromucous of snail and chitosan as an alternative anti-tuberculosis drugs. Asian Journal of Pharmaceutical and Clinical Research. 13(10):44-9. https://doi.org/10.22159/ajpcr.2020.v13i10.38266
Sutanto, Y.S., Magdalena S., Agnes S.H, Nony P. (2021). The Sensitivity Test of Mycobacterium tuberculosis to Snail Seromucoid and Chitosan in vitro. Jurnal Biomedika 14 (1)36-45 http://ejurnal. setiabudi.ac.id/ojs/index.php/biomedika/ article/view/1128
Sutanto, Y.S., Harti, A.S, Sutanto, M., Puspawati, N., (2021). The Effectiveness Antimicrobial of Polysaccharide Gel from Durian Peel Etanol Extract and Chitosan Gel. Proceeding the 7th International Conference on Biological Sciences (ICBS 2021), Oct 14-15 th, 2021. Faculty of Biology, Universitas Gadjah Mada, Yogyakarta.
Widyaartha, GNAZ, dkk., 2020. Pendekatan Simplez Lattice Design pada Formulasi Wound Dressing Gel Pentoxifylline dengan Kombinasi Gelling Agent HPMC dan Chitosan. Act Holis Pharm. 2020. 2(2): 28-36
