Nutritional Analysis of Aqueous Extract of Snake Fruit Seeds (Salacca Edulis Reinw) for Development of Anemia Treatment
Abstract
Anemia remains a global nutritional problem, which prevalence continues to increase every year. Children, female adolescents, and pregnant women are more susceptible to anemia than other age groups. Prolonged anemia has negative impacts on their life such as premature birth, low birth weight (LBW) babies and intrauterine fetal death. Snake fruit Pondoh (Salacca edulis Reinw) is an original Indonesian fruit, which is well cultivated at the Sleman regency, Yogyakarta. Snake fruit seeds contribute to 25-30% of the total fruit, which has not been established their health effect. Therefore, this study aims to analyze the nutritional content of aqueous extract of snake fruit seeds (AES). The powder of snake fruit seeds was made using a previous method, which was adopted from our research group. The powder was then extracted using hot aqueous with 65°C. A proximate analysis was used to determine the AES nutritional content. A hundred g AES contained 21.92% water, 41.10% carbohydrates, 12.66% protein, 4.51% fat, 0.62% tannins, 32.8 mg Iron, 10.25 mg zinc, 276.42 mg magnesium, and 495.48 mg vitamin C. In conclusion, the AES has complete macronutrients and contains high levels of Iron, Magnesium, and vitamin C, which becomes a potential nutraceutical for anemia treatment. Further research is required to confirm the beneficial effect of AES administration in female rats with anemia.
References
Ganz, T. 2013. Systemic Iron Homeostasis. Physiol Rev 93, pp. 1721–1741. Available at: www.prv.org.
Gusti, I., Sriningrat, A.A., Cintya, P., Yuliyatni, D. and Ani, L.S. 2019. Prevalensi Anemia Pada Remaja Putri Di Kota Denpasar. Jurnal Medika 8(2), pp. 1–6. Available at: https://ojs.unud.ac.id/index.php/eum.
Huang, J., Xu, J., Ye, P. and Xin, X. 2023. Association between magnesium intake and the risk of anemia among adults in the United States. Frontiers in Nutrition 10. doi: 10.3389/fnut.2023.1046749.
Ismail, A.A. and Ismail, N.A. 2016. Magnesium: A Mineral Essential for Health Yet Generally Underestimated or Even Ignored. Journal of Nutrition & Food Sciences 6(4). doi: 10.4172/2155-9600.1000523.
Jeng, S.S. and Chen, Y.H. 2022. Association of Zinc with Anemia. Nutrients 14(22). doi: 10.3390/nu14224918.
Karasu, E., Erol, M., Yiğit, Ö. and Gayret, Ö.B. 2018. Serum zinc level in iron deficiency and iron deficiency anemia of children aged 6 months to 5 years. Progress in Nutrition 20(1), pp. 59–66. doi: 10.23751/pn.v20i1.5201.
KEMENKES. 2019. Peraturan Menteri Kesehatan Republik Indonesia.
KEMENKES. 2023. Kemenkes-Ri-Vitamin-C.
KEMENKES RI. 2018. Riskesdas 2018.
Krawiec, P. and Pac-Kożuchowska, E. 2020. Biomarkers and hematological indices in the diagnosis of iron deficiency in children with inflammatory bowel disease. Nutrients 12(5). doi: 10.3390/nu12051358.
Krisnanda, R. 2020. Vitamin C Membantu Dalam Absorpsi Zat Besi Pada Anemia Defisiensi Besi. Available at: http://jurnal.globalhealthsciencegroup.com/index.php/JPPP.
Kumar, A., Sharma, E., Marley, A., Samaan, M.A. and Brookes, M.J. 2022. Iron deficiency anaemia: Pathophysiology, assessment, practical management. BMJ Open Gastroenterology 9(1). doi: 10.1136/bmjgast-2021-000759.
Natasia, K., Indarto, D. and Wasita, B. 2021. Fractionation of Snake Fruit Seeds Pondoh for Development of Anemia Treatment. European Alliance for Innovation n.o. doi: 10.4108/eai.17-7-2021.2312402.
Piskin, E., Cianciosi, D., Gulec, S., Tomas, M. and Capanoglu, E. 2022. Iron Absorption: Factors, Limitations, and Improvement Methods. ACS Omega 7(24), pp. 20441–20456. doi: 10.1021/acsomega.2c01833.
Plaza, M. and Turner, C. 2015. Pressurized hot water extraction of bioactives. TrAC - Trends in Analytical Chemistry 71, pp. 39–54. doi: 10.1016/j.trac.2015.02.022.
Ristanti, I.K., Tamtomo, D.G. and Indarto, D. 2019. Immunological Responses in Female Rats Model with Anemia Treated with Snake Fruit Seed Flour Extract. In: Journal of Physics: Conference Series. Institute of Physics Publishing. doi: 10.1088/1742-6596/1374/1/012038.
Suharni, S., Indarto, D. and Cilmiaty, R. 2021. Comparison of Ethanol and Methanol Extracts of Bay Leaves (Syzygium polyanthum) in Terms of Vitamin C, Iron and Phytochemical Levels. European Alliance for Innovation n.o. doi: 10.4108/eai.17-7-2021.2312403.
Sukmawati V, S.D. 2013. Daya Antibakteri Dekokta Kulit Buah Delima Putih (Granati fructus cortex) terhadap Spreptococcus mutans. Artikel Ilmiah Hasil Penelitian Mahasiswa, pp. 1–4.
Susanti, T., Dirgahayu, P. and Indarto, D. 2018. Development of Rat Model with Iron Deficiency Anemia by Modification of Its Standard Food. Atlantis Press. doi: 10.2991/phico-17.2018.22.


