Literature Review: Psychosocial Aspects as Determinants of Cancer Patients' Quality of Life

  • Umi Khudoifah Universitas Islam Sultan Agung
  • Herry Susanto Universitas Islam Sultan Agung
  • Ahmad Ikhlasul Amal Universitas Islam Sultan Agung
  • Suyanto Suyanto Universitas Islam Sultan Agung
Keywords: cancer patients, psychosocial factors, quality of life

Abstract

Cancer is a chronic disease that not only affects patients physically, but also causes significant psychosocial distress. These psychosocial aspects have been shown to reduce patients' quality of life, yet are often overlooked in clinical practice. In fact, psychosocial-based interventions can strengthen emotional resilience and improve overall therapeutic outcomes. This review aims to evaluate the contribution of psychosocial aspects to cancer patients' quality of life based on recent scientific literature. This study was a systematic literature review by searching articles from two major databases, namely PubMed and Google Scholar, within the period 2020-2025. The search strategy was organized based on the PICO framework using keywords such as “psychosocial factors”, “quality of life”, and “cancer patients”. From a total of 180 articles found, 28 duplicate articles were eliminated, leaving 152 unique articles. The next stage of screening was done by reviewing the titles and abstracts, so 79 irrelevant articles were excluded and 73 articles continued to the next stage. At the eligibility assessment stage, 32 articles were selected after full-text reading and evaluation based on the inclusion criteria, which included discussing the relationship between psychosocial aspects and the quality of life of cancer patients, being available in full-text format, and written in either English or Indonesian. Finally, an in-depth evaluation of the quality and relevance of the articles was conducted, resulting in only 10 articles being deemed eligible for analysis in this literature review. The literature review indicated that psychosocial aspects such as anxiety, depression, coping, social support, and spirituality were shown to determine the quality of life of cancer patients. Psychosocial aspects are important determinants of cancer patients' quality of life.

References

Belau, Matthias Hans, Jung, Lisa, Maurer, Tabea, Obi, Nadia, Behrens, Sabine, Seibold, Petra, Becher, Heiko, & Chang‐Claude, Jenny. (2024). Social relationships and their impact on health‐related quality of life in a long‐term breast cancer survivor cohort. Cancer, 130(18), 3210–3218. https://doi.org/10.1002/cncr.35364

Bergerot, Cristiane, Jacobsen, Paul B., Rosa, William E., Lam, Wendy Wing Tak, Dunn, Jeff, Fernández-González, Loreto, Mehnert-Theuerkauf, Anja, Veeraiah, Surendran, & Li, Madeline. (2024). Global unmet psychosocial needs in cancer care: health policy. EClinicalMedicine, 78, 102942. https://doi.org/10.1016/j.eclinm.2024.102942

Dewi, Rizka Amalia, Mudigdo, Ambar, & Pamungkasari, Eti Poncorini. (2020). Path Analysis on the Biopsychosocial Factors Affecting the Quality of Life in Patients with Breast Cancer. Journal of Epidemiology and Public Health, 5(1), 119–131. https://doi.org/10.26911/jepublichealth.2020.05.01.12

Ding, Yiqian, Wang, Xin, Zhang, Fan, Yan, Hao, Liu, Yaoyao, & Zhang, Lan. (2024). The relationship between perceived social support, coping style, and the quality of life and psychological state of lung cancer patients. BMC Psychology, 12(1), 439. https://doi.org/10.1186/s40359-024-01927-y

Dong, Ruishu, Mohamad Aun, Nur Saadah, Sofia Amin, Aizan, & Hassan, Nazirah. (2025). Psychosocial Factors Promoting Resilience in Breast Cancer Survivors: A Qualitative Study. Sage Open, 15(1). https://doi.org/10.1177/21582440251323654

Ebob-Anya, Bachi-Ayukokang, & Bassah, Nahyeni. (2022a). Psychosocial distress and the quality of life of cancer patients in two health facilities in Cameroon. BMC Palliative Care, 21(1), 96. https://doi.org/10.1186/s12904-022-00981-w

Ebob-Anya, Bachi-Ayukokang, & Bassah, Nahyeni. (2022b). Psychosocial distress and the quality of life of cancer patients in two health facilities in Cameroon. BMC Palliative Care, 21(1), 96. https://doi.org/10.1186/s12904-022-00981-w

Khalilnejad, Nahid, Asgari, Parviz, Ahmadian, Hamzeh, & Shahrbabaki, Heydar Eslami. (2025). The Effectiveness of Quality of Life Therapy on Psychological Well-Being and Social Adjustment in Breast Cancer Patients. The Journal of Tolooebehdasht. https://doi.org/10.18502/tbj.v23i5.17665

Kovac, Aleksandra, Tovilovic, Snezana, Bugarski-Ignjatovic, Vojislava, Popovic-Petrovic, Svetlana, & Tatic, Milanka. (2020). The role of cognitive emotion regulation strategies in health related quality of life of breast cancer patients. Vojnosanitetski Pregled, 77(10), 1032–1040. https://doi.org/10.2298/VSP180205178K

Ladesvita, Fiora, & Sari, Selvy Juwita. (2023). ACTIVITY DAILY LIVING DAN QUALITY OF LIFE PASIEN KANKER YANG MENJALANI KEMOTERAPI. Indonesian Journal of Health Development, 5(1), 30–38. https://doi.org/10.52021/ijhd.v5i1.115

Lan, Bo, Lv, Dan, Yang, Min, Sun, Xiaoying, Zhang, Li, & Ma, Fei. (2022). Psychological symptoms and quality of life in Chinese early-stage breast cancer patients throughout chemotherapy. Journal of Clinical Oncology, 40(16_suppl), e24145–e24145. https://doi.org/10.1200/JCO.2022.40.16_suppl.e24145

Lantheaume, Sophie, Fernandez, Lydia, Lantheaume, Stéphane, Moták, Ladislav, & Conceição, Stéphanie Blois-Da. (2022). Quality of life in patients with non-metastatic breast cancer: evolution during follow-up and vulnerability factors. Supportive Care in Cancer, 30(3), 1935–1943. https://doi.org/10.1007/s00520-021-06203-y

Mustață, Laura Mihaela, Peltecu, Gheorghe, Gică, Nicolae, Botezatu, Radu, Iancu, George, Gheoca, George Dumitru, Cigăran, Ruxandra, & Iordăchescu, Diana Antonia. (2024). Evaluation of quality of life and socio-emotional impact of oncological treatment among patients with breast cancer. Journal of Medicine and Life, 17(3), 341–352. https://doi.org/10.25122/jml-2024-0238

R., Ratna, Supadmi, Woro, & Yuniarti, Endang. (2021). Kualitas Hidup Pasien Kanker Rawat Jalan yang Menjalani Kemoterapi di RSUD Kota Yogyakarta. Majalah Farmaseutik, 17(2). https://doi.org/10.22146/farmaseutik.v17i2.62832

Rahi Singh Bhim, & Chaudhary Sunil. (2022). Assessment of Psychosocial Effect and Quality of Life in Breast Cancer Patients. Mind & Society, 11(01), 54–61.

Sung, Hyuna, Ferlay, Jacques, Siegel, Rebecca L., Laversanne, Mathieu, Soerjomataram, Isabelle, Jemal, Ahmedin, & Bray, Freddie. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/caac.21660

Tresnawati, Lena, & Erwandi, Dadan. (2021). Kajian Literatur Sistematis Faktor Psikososial yang Berhubungan dengan Risiko Psikososial pada Pekerja. Health Information : Jurnal Penelitian, 13(2), 151–164. https://doi.org/10.36990/hijp.v13i2.417

Yuliawati Nila Agustina, Dewanti Putu Natasya Ni, & Ratnasari Made Desy Pande. (2024). Quality of Life of Breast Cancer Patients Undergoing Chemotherapy and Factors Affecting It at Gianyar Hospital. Farmasi: Jurnal Farmasi Indonesia, 206–218.

Zhu, Hanjing, Yang, Linning, Yin, Hongfan, Yuan, Xia, Gu, Jia, & Yang, Yan. (2024a). The Influencing Factors of Psychosocial Adaptation of Cancer Patients: A Systematic Review and Meta-Analysis. Health Services Insights, 17. https://doi.org/10.1177/11786329241278814

Zhu, Hanjing, Yang, Linning, Yin, Hongfan, Yuan, Xia, Gu, Jia, & Yang, Yan. (2024b). The Influencing Factors of Psychosocial Adaptation of Cancer Patients: A Systematic Review and Meta-Analysis. Health Services Insights, 17. https://doi.org/10.1177/11786329241278814

Published
2025-08-01
How to Cite
Khudoifah, U., Susanto, H., Amal, A. I., & Suyanto, S. (2025). Literature Review: Psychosocial Aspects as Determinants of Cancer Patients’ Quality of Life. Indonesian Journal of Global Health Research, 7(4), 759-766. https://doi.org/10.37287/ijghr.v7i4.6473

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