The Benefits of Diabetes Self Management Education (DSME) on Glycemic Control (HBA1C) Among Adult Type 2 Diabetes Mellitus Patients in Southeast Asia: A Systematic Review
Abstract
The number of people with Type 2 Diabetes Mellitus (T2DM) in Southeast Asia ranks second highest compared to other regions in the world. Lifestyle modification is known to be significant in controlling glycemic control in T2DM patients. Diabetes Self-Management Education (DSME), which includes lifestyle changes such as diet modification and physical activity, has been implemented in healthcare facilities in Southeast Asian countries. Nevertheless, evidence on the advantage of DSME for patients with T2DM in Asia Tenggara remains limited. This systematic review aims to determine the benefits of DSME on glycemic control (HbA1c) among T2DM patients in Southeast Asia. This systematic review searched for relevant articles from three electronic databases, i.e., MEDLINE (PubMed), ProQuest, and Cochrane from 01 Januari 2013 until 30 December 2024. The inclusion criteria for this review are studies with a randomized controlled trial (RCT) design that evaluate the effect of DSME interventions on glycemic control (HbA1c) in patients with T2DM in Southeast Asian countries. Quality of the included studies were assessed using the Risk of Bias (RoB 2.0) Cochrane Methods Bias. A total of 474 studies were identified from the databases, of which six RCT met the inclusion criteria. The review results showed that patients who received at least 3 months of intervention with lifestyle change education, including both diet modification and physical activity, showed a significant reduction in HbA1c. Educational interventions focusing on self-efficacy, particularly in diet modification, effectively reduced HbA1c by 1.1% after 3 months. The benefit of DSME on reduction of HbA1c varied across the different type of interventions. DSME leads to positive effect on glycemic control among patients with T2DM. The diversity of DSME highlights the need for further evaluation of the impact of different types of DSME on the effectivseness of education in achieving long-term HbA1c reduction. PROSPERO registration number: CRD42025634450.
References
Adu, F. A., Poku, C. A., Adu, A. P., & Owusu, L. B. (2024). The role of social support and self‐management on glycemic control of type 2 diabetes mellitus with complications in Ghana: A cross‐sectional study. Health Science Reports, 7(4), e2054. https://doi.org/10.1002/hsr2.2054
Cassidy, D., & Chinna, K. (2017). Depression, distress and self-efficacy: The impact on diabetes self-care practices. PLOS ONE, 12(3), e0175096. https://doi.org/10.1371/journal.pone.0175096
Chan, S. P., Aamir, A. H., Bee, Y. M., Deerochanawong, C., Paz-Pacheco, E., Tiu, F., Foo, S. H., Tan, K. E. K., Le, T. Q., Saraswati, M. R., Bunnag, P., Panusunan Sibarani, R., Raza, S. A., & Tran, N. Q. (2022). Practical Guidance on Basal Insulin Initiation and Titration in Asia: A Delphi-Based Consensus. Diabetes Therapy, 13(8), 1511–1529. https://doi.org/10.1007/s13300-022-01286-0
Chandran, R. S., Rahman, N., Gandhi, M., Tan, N. C., Phoon, I. K. Y., Seah, D. E. J., Cheah, M. H., Sek, K., & Gardner, D. S.-L. (2024). Intermittently scanned continuous glucose monitoring provides no benefit over structured self-monitoring of blood glucose in type 2 diabetes not on prandial insulin, in the context of diabetes self-management education: GLucose monitoring programme SingaporE (GLiMPSE). Diabetes Research and Clinical Practice, 211, 111678. https://doi.org/10.1016/j.diabres.2024.111678
Changsieng, P., Pichayapinyo, P., Lagampan, S., & Lapvongwatana, P. (2023). Implementation of Self-Care Deficits Assessment and a Nurse-Led Supportive Education Program in Community Hospitals for Behavior Change and HbA1c Reduction: A Cluster Randomized Controlled Trial.
Chanpiwat, P., & Kim, K.-W. (2019). Arsenic health risk assessment related to rice consumption behaviors in adults living in Northern Thailand. Environmental Monitoring and Assessment, 191(11), 674. https://doi.org/10.1007/s10661-019-7836-y
Chew, B., Khoo, E., & Chia, Y. (2015). Social Support and Glycemic Control in Adult Patients With Type 2 Diabetes Mellitus. Asia Pacific Journal of Public Health, 27(2), NP166–NP173. https://doi.org/10.1177/1010539511431300
Cochrane Method of Bias. (2020). RoB 2: A revised Cochrane risk-of-bias tool for randomized trials | Cochrane Bias. https://methods.cochrane.org/bias/resources/rob-2-revised-cochrane-risk-bias-tool-randomized-trials
Hashiguchi, O. L., Cox, S. E., Edwards, T., Castro, M. C., Khan, M., & Liverani, M. (2023). How can tuberculosis services better support patients with a diabetes co-morbidity? A mixed methods study in the Philippines. BMC Health Services Research, 23(1), 1027. https://doi.org/10.1186/s12913-023-10015-7
IDF. (2025). IDF Diabetes Atlas 2025 Global Diabetes Data & Insights. https://diabetesatlas.org/resources/idf-diabetes-atlas-2025/
Jantraporn, R., Pichayapinyo, P., Lagampan, S., & Mayurasakorn, K. (2020). Effects of Carbohydrate Reduction Program and Telemonitoring on Glycosylated Hemoglobin in Patients with Poorly Controlled Type 2 Diabetes: A Randomized Controlled Trial.
JBI, G. (2015). JBISRIR endorses PRISMA Statement: PRISMA flow diagram. https://jbi.global/news/article/jbisrir-endorses-prisma-statement
Karki, A., Vandelanotte, C., Khalesi, S., Dahal, P., & Rawal, L. B. (2023). The effect of health behavior interventions to manage Type 2 diabetes on the quality of life in low-and middle-income countries: A systematic review and meta-analysis. PLOS ONE, 18(10), e0293028. https://doi.org/10.1371/journal.pone.0293028
Mary L, M. (2012). Interrater reliability: The kappa statistic—PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC3900052/#abstract1
Nguyen, S. N., Tran, V. D., Le, T. T. M., Nga, H. T., & Tho, N. T. T. (2021). Lifestyle Interventions Reduce the Risk of Type II Diabetes and Cardiovascular Diseases Development among Pre-diabetic Adults. International Journal Of Pharmaceutical Research And Allied Sciences, 10(2), 94–102. https://doi.org/10.51847/8RpiSiVJRG
Nielsen, K. K., Calopietro, M., Yeow, T. P., Tahir Bin Aris, & Bjerre-Christensen, U. (2020). Perceptions and Abilities Related to Patient Engagement In Diabetes Care among Primary Healthcare Providers in Malaysia: A Qualitative Study. Malaysian Journal of Public Health Medicine, 20(2), 207–214. https://doi.org/10.37268/mjphm/vol.20/no.2/art.280
Premadasa, S. S., Masingboon, K., & Samartkit, N. (2024). Diabetes self-management and its influencing factors among adults with type 2 diabetes mellitus in rural Sri Lanka: A cross-sectional study. Belitung Nursing Journal, 10(4), 448–455. https://doi.org/10.33546/bnj.3441
PROSPERO, N. (2025). International prospective register of systematic reviews. https://www.crd.york.ac.uk/prospero/
Purwonugroho, T. A., Budi, R., Laksmi, M., Ika, M., Vitis Vini Fera Ratna, U., Githa Fungi, G., Hanif Nasiatul, B., Hening, P., Pugud, S., Jamaludin Al J., E., & Didik, S. (2021). Community pharmacist home visit-based intervention improved diabetes patients’ outcomes: A randomized controlled trial. Journal of Applied Pharmaceutical Science. https://doi.org/10.7324/JAPS.2021.110306
Review Manager. (2023). RevMan. In (Version 5.4.1) Cochrane Training. https://training.cochrane.org/online-learning/core-software
Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., & Stewart, L. A. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: Elaboration and explanation. https://doi.org/10.1136/bmj.g7647
Singh, G. H. K., Chee, W. S. S., Hamdy, O., Mechanick, J. I., Lee, V. K. M., Barua, A., Mohd Ali, S. Z., & Hussein, Z. (2020). Eating self-efficacy changes in individuals with type 2 diabetes following a structured lifestyle intervention based on the transcultural Diabetes Nutrition Algorithm (tDNA): A secondary analysis of a randomized controlled trial. PLOS ONE, 15(11), e0242487. https://doi.org/10.1371/journal.pone.0242487
Thanh, H. T. K., & Tien, T. M. (2021). Effect of Group Patient Education on Glycemic Control Among People Living with Type 2 Diabetes in Vietnam: A Randomized Controlled Single-Center Trial. Diabetes Therapy, 12(5), 1503–1521. https://doi.org/10.1007/s13300-021-01052-8
Xue, H., Li, M., Fan, L., Zou, J., Yang, B., & Du, W. (2024). Metformin-Related Adverse Drug Reactions Among Rural and Urban Adults Aged 45 Years and Older in Jiangsu Province of China, 2010-2020. Asia Pacific Journal of Public Health, 36(1), 146–149. https://doi.org/10.1177/10105395231207675
Yeemard, F., Srichan, P., Apidechkul, T., Luerueang, N., Tamornpark, R., & Utsaha, S. (2022). Prevalence and predictors of suboptimal glycemic control among patients with type 2 diabetes mellitus in northern Thailand: A hospital-based cross-sectional control study. PLOS ONE, 17(1), e0262714. https://doi.org/10.1371/journal.pone.0262714
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