The Relationship between HIV Human Immunodeficiency Virus and the Incidence of Tuberculosis (TB)
Abstract
HIV and Tuberculosis are a deadly combination, these two diseases accelerate the development of each other. The combination of these two infectious diseases influences each other in all aspects of the disease. Objective to determine the relationship between HIV (Human immunodeficiency virus) and the incidence of tuberculosis. Method: to determine the relationship between HIV (Human immunodeficiency virus) and the incidence of tuberculosis. Research methods : The research design used was analytical observational with a cross sectional approach. The population in this study were all HIV sufferers who were undergoing inpatient treatment in the UPIPI Room at Dr. RSUD. Soetomo. The sampling technique uses total sampling. The independent variable in this study is HIV sufferers. The dependent variable in this study is the incidence of tuberculosis. Data analysis used the Spearman Rank test with significance <0.05. Result : The research design used was observational analytics with a cross sectional approach. The population in this study were all HIV sufferers who were undergoing inpatient treatment in the UPIPI Room at Dr. RSUD. Soetomo. The sampling technique uses total sampling. The independent variable in this research is HIV sufferers. The dependent variable in this research is the incidence of tuberculosis. Data analysis using the Rank Spearman test with significance <0.05. Conclusions : Tuberculosis infection in HIV patients is closely related to a decrease in the immune system. As the stage of HIV increases, the body's immune system will decrease, so this can increase the risk of opportunistic infection with tuberculosis. The best way to prevent opportunistic infections is to avoid exposing HIV-infected people to tuberculosis.
References
Abdallah, T. M., & Ali, A. A. A. (2012). Epidemiology of tuberculosis in Eastern Sudan. Asian Pacific Journal of Tropical Biomedicine, 2(12), 999–1001. https://doi.org/10.1016/S2221-1691(13)60013-1
Andri, A. J., Poerwandar, E. K., & Bintari, D. R. (2013). Understanding Drug Abusers with HIV/AIDS through Qualitative Research. Makara Human Behavior Studies in Asia, 17(1), 64. https://doi.org/10.7454/mssh.v17i1.1803
Bates, M. N., Khalakdina, A., Pai, M., Chang, L., Lessa, F., & Smith, K. R. (2007). Risk of tuberculosis from exposure to tobacco smoke: A systematic review and meta-analysis. Archives of Internal Medicine, 167(4), 335–342. https://doi.org/10.1001/archinte.167.4.335
Cahyati, W. H. (2019). Determinan Kejadian Tuberkulosis pada Orang dengan HIV/AIDS. 3(2), 168–178.
Dalbo, M., & Tamiso, A. (2016). Incidence and Predictors of Tuberculosis among HIV/AIDS Infected Patients: A Five-Year Retrospective Follow-Up Study. Advances in Infectious Diseases, 06(02), 70–81. https://doi.org/10.4236/aid.2016.62010
Diedrich, C. R., & Flynn, J. L. (2011). MINIREVIEW HIV-1 / Mycobacterium tuberculosis Coinfection Immunology : How Does HIV-1 Exacerbate Tuberculosis ? ᰔ. 79(4), 1407–1417. https://doi.org/10.1128/IAI.01126-10
Djalilah, G. N., & Subagyo, R. (2021). Hubungan Perilaku Seksual Berisiko dengan Kejadian HIV / AIDS Pada Laki Seks Laki The Relationship between Risky Sexual Behavior With the Incidence Of HIV / AIDS Among Men Who Have Sex With Men. 2(1).
Ekwaru, J. P., Campbell, J., Malamba, S., Moore, D. M., Were, W., & Mermin, J. (2013). The effect of opportunistic illness on HIV RNA viral load and CD4+ T cell count among HIV-positive adults taking antiretroviral therapy. Journal of the International AIDS Society, 16(May 2003), 1–6. https://doi.org/10.7448/IAS.16.1.17355
Fauzia, Mahmuda, G. (2020). Hasil Pemeriksaan Kadar Cd4 Dan Tcm Genexpert Mtb. 6(2), 144–150.
Framasari, D. A., Flora, R., & Sitorus, R. J. (2020). Infeksi Oportunistik pada ODHA Terhadap Kepatuhan Minum ARV di Kota Palembang. JAMBI MEDICAL JOURNAL “Jurnal Kedokteran Dan Kesehatan,” 8(1), 67–74.
Kedzierska, K., Crowe, S. M., Turville, S., & Cunningham, A. L. (2003). The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages. Reviews in Medical Virology, 13(1), 39–56. https://doi.org/10.1002/rmv.369
Kemenkes, Ri. (2017). Data dan Informasi Kesehatan Indonseia 2016.
Kemenkes, Ri. (2018). Profil Kesehatan Indonesia 2016.
Liebert, M. A., Coreceptors, U., Rosas-taraco, A. G., Arce-mendoza, A. Y., Caballero-olín, G., & Salinas-carmona, M. C. (2006). Mycobacterium tuberculosis. 22(1), 45–51.
Marfidhotul Iftitah, N., Adi, S., & Warih Gayatri, R. (2020). Faktor Yang Mempengaruhi Terjadinya Ko-Infeksi Tuberculosis Pada Pasien Hiv/Aids Di Kabupaten Malang. Preventia: Indonesian Journal of Public Health, 5(1), 27–34.
M., Corbett, L., Getahun, H., Kittikraisak, W., Heilig, C. M., Corbett, E. L., Ayles, H., Cain, K. P., Grant, A. D., Churchyard, G. J., Kimerling, M., Shah, S., Stephen, D., Wood, R., Maartens, G., Granich, R., Date, A. A., & Varma, J. K. (2011). Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource-Constrained Settings : Individual Participant Data Development of a Standardized Screening Rule for Tuberculosis in People Living with HIV in Resource- Con. January. https://doi.org/10.1371/journal.pmed.1000391
Patel, N. R., Zhu, J., Tachado, S. D., Zhang, J., Wan, Z., Saukkonen, J., Koziel, H., & Elisa, N.-B. (2007). HIV Impairs TNF-_ Mediated Macrophage Apoptotic Response to Mycobacterium tuberculosis.
Permitasari, D. A. (2012). Tuberkulosis Pada Pasien Hiv / Aids Di Rsup Dr . Kariadi Semarang Jurnal Media Medika Muda.
Pradipta, A., Korib Sudaryo, M., Rusli, A., Studi Kesehatan Masyarakat, P., Kesehatan Masyarakat Universitas Indonesia, F., Sulianti Saroso, R., Kesehatan Republik Indonesia, K., & Penulis, K. (2015). Faktor-Faktor yang Berhubungan dengan Infeksi Oportunistik Tuberkulosis pada Pasien HIV di RSPI Sulianti Saroso Tahun. The Indonesian Journal of Infectious Disease, 6(2), 18–30.
Pustil, R. L. (2017). Global AIDS. AIDS (London, England), 17 Suppl 4. https://doi.org/10.1097/00002030-199001001-00040
Rafael, S., & Nabire, K. (2021). Profil Pasien HIV / AIDS dengan Koinfeksi Tuberkulosis di Puskesmas Bumi Wonorejo dan Klinik. 31(4), 247–252.
Roselinda, R., & Setiawaty, V. (2016). The stages of HIV infection and the risk of opportunistic Tuberculosis infection. Health Science Journal of Indonesia, 6(2), 121–125. https://doi.org/10.22435/hsji.v6i2.4771.121-125
Rottenberg, M. E., Pawlowski, A., Jansson, M., & Sko, M. (2012). Tuberculosis and HIV Co-Infection. 8(2). https://doi.org/10.1371/journal.ppat.1002464
Tornheim, J. A., & Dooley, K. E. (2017). Tuberculosis Associated with HIV Infection. https://doi.org/10.1128/microbiolspec.TNMI7-0028-2016.Correspondence
WHO. (2017). Global Tuberculosis Reposrt 2017.
Wijaya, I. M. K. (2013). Infeksi Hiv ( Human Immunodeficiency Virus ) Pada Penderita Tuberkulosis. Seminar Nasional FMIPA UNDIKSHA III, 3, 295–303. http://ejournal.undiksha.ac.id/index.php/semnasmipa/article/view/2721/2301
Winter, J. R., Smith, C. J., Davidson, J. A., Lalor, M. K., Delpech, V., Abubakar, I., & Stagg, H. R. (2020). The impact of HIV infection on tuberculosis transmission in a country with low tuberculosis incidence : a national retrospective study using molecular epidemiology. 1–15.
Copyright (c) 2024 Indonesian Journal of Global Health Research

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.



