Faktor-faktor yang Mempengaruhi Kadar Hemoglobin pada Wanita Prakonsepsi: Studi Kasus Kontrol
Abstract
Kesehatan wanita pada masa prakonsepsi merupakan langkah untuk melindungi kesehatan ibu dan anak yang mungkin terjadi di kemudian hari. Pemeriksaan hemoglobin sebelum kehamilan dilakukan untuk menghindari anemia. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kadar hemoglobin pada wanita prakonsepsi. Penelitian ini menggunakan metode observasional dengan rancangan studi kasus-kontrol yang melibatkan 118 calon pengantin prakonsepsi dan dilaksanakan di Kantor Urusan Agama Provinsi Sulawesi Selatan, Indonesia, pada bulan Juli 2022. Sampel penelitian diklasifikasikan menjadi kelompok kadar hemoglobin rendah (59 responden) dan kelompok kadar hemoglobin normal (59 responden). Sampel dipilih secara purposive sampling sesuai dengan kriteria inklusi dan eksklusi. Data dikumpulkan menggunakan lembar kuesioner, food recall 24 jam dan hasil sampel darah kapiler. Analisis data menggunakan uji chi-square. Hasil analisis menunjukkan bahwa usia, pendidikan, status gizi, dan status ekonomi berkorelasi signifikan dengan kadar hemoglobin pada wanita prakonsepsi (P < 0,05). Pada regresi logistik, faktor yang berhubungan dengan hemoglobin adalah usia (OR 13,162), status gizi (OR 11,416), dan pendidikan (OR 0,018). Usia, pendidikan, status gizi, dan status ekonomi dapat memengaruhi kadar hemoglobin pada wanita prakonsepsi. Usia dan status gizi merupakan faktor yang paling berpengaruh.
References
Adamu, A. L., Crampin, A., Kayuni, N., Amberbir, A., Koole, O., Phiri, A., Nyirenda, M., & Fine, P. (2017). Prevalence and Risk Factors for Anemia Severity and Type in Malawian Men and Women: Urban and Rural Differences. Population Health Metrics, 15(1), 12. https://doi.org/10.1186/s12963-017-0128-2
Adu, P., Attivor, W., Nartey, S. T., Ephraim, R. K. D., & Awuku, Y. A. (2020). Low Iron Stores in Preconception Nulliparous Women; aTtwo-Center Cross-Sectional Study in Peri-Urban Ghana. Nutrition, 71, 110604. https://doi.org/10.1016/j.nut.2019.110604
Ahmed, M. H., Ghatge, M. S., & Safo, M. K. (2020). Hemoglobin: Structure, Function and Allostery (pp. 345–382). https://doi.org/10.1007/978-3-030-41769-7_14
Al-alimi, A. A., Bashanfer, S., & Morish, M. A. (2018). Prevalence of Iron Deficiency Anemia among University Students in Hodeida Province, Yemen. Anemia, 2018, 1–7. https://doi.org/10.1155/2018/4157876
AlFaris, N., ALTamimi, J., AlKehayez, N., AlMushawah, F., AlNaeem, A., AlAmri, N., AlMudawah, E., Alsemari, M., Alzahrani, J., Alqahtani, L., Alenazi, W., Almuteb, A., & Alotibi, H. (2021). Prevalence of Anemia and Associated Risk Factors Among Non-Pregnant Women in Riyadh, Saudi Arabia: A Cross-Sectional Study. International Journal of General Medicine, Volume 14, 765–777. https://doi.org/10.2147/IJGM.S299450
Berhe, B., Mardu, F., Legese, H., Gebrewahd, A., Gebremariam, G., Tesfay, K., Kahsu, G., Negash, H., & Adhanom, G. (2019). Prevalence of Anemia and Associated Factors among Pregnant Women in Adigrat General Hospital, Tigrai, northern Ethiopia, 2018. BMC Research Notes, 12(1), 310. https://doi.org/10.1186/s13104-019-4347-4
Bolka, A., & Gebremedhin, S. (2019). Prevalence of Intestinal Parasitic Infection and its Association with Anemia among Pregnant Women in Wondo Genet District, Southern Ethiopia: a Cross-Sectional Study. BMC Infectious Diseases, 19(1), 483. https://doi.org/10.1186/s12879-019-4135-8
Chaparro, C. M., & Suchdev, P. S. (2019). Anemia Epidemiology, Pathophysiology, and Etiology in Low‐ and Middle‐Income Countries. Annals of the New York Academy of Sciences, 1450(1), 15–31. https://doi.org/10.1111/nyas.14092
Chowdhury, R., Taneja, S., Dhabhai, N., Mazumder, S., Upadhyay, R. P., Sharma, S., Tupaki-Sreepurna, A., Dewan, R., Mittal, P., Chellani, H., Bahl, R., Bhan, M. K., & Bhandari, N. (2020). Burden of Preconception Morbidity in Women of Reproductive Age from an Urban Setting in North India. PLOS ONE, 15(6), e0234768. https://doi.org/10.1371/journal.pone.0234768
Edison, E. E. (2019). Relationship between Education Level and Anemia Incidence in Pregnant Women. Jurnal JKFT, 4(2), 65–71. https://doi.org/10.31000/jkft.v4i2.2502
Fentie, K., Wakayo, T., & Gizaw, G. (2020). Prevalence of Anemia and Associated Factors among Secondary School Adolescent Girls in Jimma Town, Oromia Regional State, Southwest Ethiopia. Anemia, 2020, 1–11. https://doi.org/10.1155/2020/5043646
Fithra Dieny, F., Khaira Maadi, A., Sandi Wijayanti, H., Arif Tsani, A. F., & Choirunissa, C. (2019). Nutrient Intake and Hemoglobin Levels of Preconception Women in Semarang District. Indonesian Journal of Human Nutrition, 6(2), 70–83. https://doi.org/10.21776/ub.ijhn.2019.006.02.2
Ghosh, S., Spielman, K., Kershaw, M., Ayele, K., Kidane, Y., Zillmer, K., Wentworth, L., Pokharel, A., Griffiths, J. K., Belachew, T., & Kennedy, E. (2019). Nutrition-Specific and Nutrition-Sensitive Factors Associated with Mid-Upper Arm Circumference as a Measure of Nutritional Status in Pregnant Ethiopian Women: Implications for programming in the First 1000 Days. PLOS ONE, 14(3), e0214358. https://doi.org/10.1371/journal.pone.0214358
Heydarpour, F., Soltani, M., Najafi, F., Tabatabaee, H. R., Etemad, K., Hajipour, M., Babanejad, M., Valadbeigi, T., Yaghoobi, H., & Rezaeian, S. (2019). Maternal Anemia in Various Trimesters and Related Pregnancy Outcomes: Results from a Large Cohort Study in Iran. Iranian Journal of Pediatrics, 29(1), e69741. https://doi.org/10.5812/ijp.69741
Jacob, C. M., Killeen, S. L., McAuliffe, F. M., Stephenson, J., Hod, M., Diaz Yamal, I., Malhotra, J., Mocanu, E., McIntyre, H. D., Kihara, A. B., Ma, R. C., Divakar, H., Kapur, A., Ferriani, R., Ng, E., Henry, L., Van Der Spuy, Z., Rosenwaks, Z., & Hanson, M. A. (2020). Prevention of Noncommunicable Diseases by Interventions in the Preconception Period: A FIGO Position Paper for Action by Healthcare Practitioners. International Journal of Gynecology & Obstetrics, 151(S1), 6–15. https://doi.org/10.1002/ijgo.13331
Kejo, D., Petrucka, P., Martin, H., Kimanya, M., & Mosha, T. (2018). Prevalence and Predictors of Anemia Among Children Under 5 Years of Age in Arusha District, Tanzania. Pediatric Health, Medicine and Therapeutics, Volume 9, 9–15. https://doi.org/10.2147/PHMT.S148515
Kumera, G., Gedle, D., Alebel, A., Feyera, F., & Eshetie, S. (2018). Undernutrition and Its Association with Socio-Demographic, Anemia and Intestinal Parasitic Infection Among Pregnant Women Attending Antenatal Care at the University of Gondar Hospital, Northwest Ethiopia. Maternal Health, Neonatology and Perinatology, 4(1), 18. https://doi.org/10.1186/s40748-018-0087-z
Lassi, Z. S., Kedzior, S. G. E., Tariq, W., Jadoon, Y., Das, J. K., & Bhutta, Z. A. (2020). Effects of Preconception Care and Periconception Interventions on Maternal Nutritional Status and Birth Outcomes in Low- and Middle-Income Countries: A Systematic Review. Nutrients, 12(3), 606. https://doi.org/10.3390/nu12030606
Mirnawati, M., Salma, W. O., & Tosepu, R. (2022). Analisis Faktor Risiko Kejadian Anemia pada Ibu Hamil. JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan, 14(3), 215–225. https://doi.org/10.36089/job.v14i3.831
Msemo, O. A., Bygbjerg, I. C., Møller, S. L., Nielsen, B. B., Ødum, L., Perslev, K., Lusingu, J. P. A., Kavishe, R. A., Minja, D. T. R., & Schmiegelow, C. (2018). Prevalence and Risk Factors of Preconception Anemia: A Community Based Cross Sectional Study of Rural Women of Reproductive Age in Northeastern Tanzania. PLOS ONE, 13(12), e0208413. https://doi.org/10.1371/journal.pone.0208413
Oh, H.-K., Kang, S., Cho, S.-H., Ju, Y., & Faye, D. (2019). Factors Influencing Nutritional Practices among Mothers in Dakar, Senegal. PLOS ONE, 14(2), e0211787. https://doi.org/10.1371/journal.pone.0211787
Purnamasari, T. (2021). Factors Associated with Knowledge of Primigravida Mothers About Anemia in Pregnancy in the Working Area of the Technical Implementation Unit of the Sukahaji Health Center Service, Majalengka Regency. Jurnal Kampus STIKES YPIB Majalengka, 8(1), 34–44. https://doi.org/10.51997/jk.v8i1.107
Rahman, Md. A., Rahman, Md. S., Aziz Rahman, M., Szymlek-Gay, E. A., Uddin, R., & Islam, S. M. S. (2021). Prevalence of and Factors Associated with Anaemia in Women of Reproductive Age in Bangladesh, Maldives and Nepal: Evidence from Nationally-Representative Survey Data. PLOS ONE, 16(1), e0245335. https://doi.org/10.1371/journal.pone.0245335
Reber, E., Gomes, F., Vasiloglou, M. F., Schuetz, P., & Stanga, Z. (2019). Nutritional Risk Screening and Assessment. Journal of Clinical Medicine, 8(7), 1065. https://doi.org/10.3390/jcm8071065
Sakwe, N., Bigoga, J., Ngondi, J., Njeambosay, B., Esemu, L., Kouambeng, C., Nyonglema, P., Seumen, C., Gouado, I., & Oben, J. (2019). Relationship between Malaria, Anaemia, Nutritional and Socio-Economic Status amongst Under-Ten Children, in the North Region of Cameroon: A Cross-Sectional Assessment. PLOS ONE, 14(6), e0218442. https://doi.org/10.1371/journal.pone.0218442
Septiasari, Y. (2019). Economic Status Plays a Role in the Incidence of Anemia in Pregnant Women at the Bernung Pesawaran Health Center. Jurnal Ilmiah Kesehatan, 8(1), 14–19. https://doi.org/10.52657/jik.v8i1.1062
Srour, M. A., Aqel, S. S., Srour, K. M., Younis, K. R., & Samarah, F. (2018). Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome. Anemia, 2018, 1–7. https://doi.org/10.1155/2018/9135625
Sukmawati, Widiasih, R., Mamuroh, L., & Nurhakim, F. (2021). Anemia of Pregnancy and its Affecting Factors: Correlation Study. Jurnal Kesehatan Bakti Tunas Husada : Jurnal Ilmu-Ilmu Keperawatan, Analis Kesehatan Dan Farmasi, 21(1), 43–53. https://doi.org/10.36465/jkbth.v21i1.679
Sumantri, A. W. (2021). Relationship between Knowledge and Education of Pregnant Women and Anemia in RT 10 RW 8 Working Area of Kemalaraja Baturaja Health Center. Jurnal Kesehatan Saelmakers PERDANA, 4(1), 51–56. https://doi.org/10.32524/jksp.v4i1.15
Sumihartini, N., Yamazaki, C., Ayu Paramita, S., Widrian Suradji, E., Koyama, H., & Hamazaki, K. (2022). Anemia and the Factors in Women of Reproductive Age: A Community-Based Study in West Papua, Indonesia. The Kitakanto Medical Journal, 72(1), 1–8. https://doi.org/10.2974/kmj.72.1
Surianti, T., & Silya, P. H. (2021). Relationship between Nutritional Status and Anemia in Pregnant Women at the Technical Implementation Unit of the Takkalalla Health Center, Wajo Regency. Jurnal Kesehatan Tambusai, 2(4), 211–218. https://doi.org/10.31004/jkt.v2i4.2562
Tesfaye, T. S., Tessema, F., & Jarso, H. (2020). Prevalence of Anemia and Associated Factors Among “Apparently Healthy” Urban and Rural Residents in Ethiopia: A Comparative Cross-Sectional Study. Journal of Blood Medicine, 11, 89–96. https://doi.org/10.2147/JBM.S239988
Utama, R. P. (2021). Nutritional Status with Anemia Incidence in Pregnant Women. Jurnal Ilmiah Kesehatan Sandi Husada, 10(2), 689–694. https://doi.org/10.35816/jiskh.v10i2.680
Whitehead, R. D., Mei, Z., Mapango, C., & Jefferds, M. E. D. (2019). Methods and Analyzers for Hemoglobin Measurement in Clinical Laboratories and Field Settings. Annals of the New York Academy of Sciences, 1450(1), 147–171. https://doi.org/10.1111/nyas.14124
Widiyanto, J., & Lismawati, G. (2019). Maternal Age and Anemia are Risk Factors of Low Birthweight of Newborn. Enfermería Clínica, 29, 94–97. https://doi.org/10.1016/j.enfcli.2018.11.010
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