The Impact of Stigma on the Mental Health of Adolescents with Tuberculosis: A Scoping Review
Abstract
Stigma toward adolescents with tuberculosis (TB) is a significant psychosocial issue that negatively affects their mental health. Adolescents are emotionally vulnerable, and the experience of stigma can exacerbate psychological distress and hinder treatment adherence. Objective: This study aims to review the scientific literature on the impact of stigma on the mental health of adolescents with tuberculosis and to identify the affected domains of mental well-being. Method: A scoping review was conducted in accordance with the PRISMA-ScR guidelines. Literature searches were performed in three major databases (Scopus, PubMed, and ScienceDirect) using the keywords “stigma,” “tuberculosis,” and “adolescent.” Articles were selected based on inclusion criteria: published between 2021 and 2025, written in english, open access, and directly relevant to the research, data extraction from the selected articles was conducted using a matrix format in microsoft word. The domains used for data extraction included the researcher’s name and year of publication, article title, research objectives, research methodology, research instruments, and key findings. Results: Out of 1,233 initially retrieved articles, 10 met the eligibility criteria and were analyzed. The synthesis of findings revealed that stigma has a detrimental impact on adolescent mental health, particularly in the forms of anxiety, depression, social withdrawal, and feelings of hopelessness. Stigma was also identified as a contributing factor to poor treatment adherence among adolescents with TB. Stigma significantly contributes to mental health challenges in adolescents diagnosed with tuberculosis. These findings highlight the urgent need for the development of multidisciplinary interventions that address psychosocial aspects to support treatment success and enhance the quality of life among adolescent TB patients.
References
Amri, N. S., Zakaria, R., & Mohamad, N. (2022). Stigma and Depression among Tuberculosis Patients in Kedah, Malaysia. IIUM Medical Journal Malaysia, 21(4), 141–149. https://doi.org/10.31436/imjm.v21i4.2055
Chen, X., Chen, Y., Zhou, L., & Tong, J. (2023). The role of self-esteem as moderator of the relationship between experienced stigma and anxiety and depression among tuberculosis patients. Scientific Reports, 13(1), 1–10. https://doi.org/10.1038/s41598-023-34129-4
Chen, X., Du, L., Wu, R., Xu, J., Ji, H., Zhang, Y., Zhu, X., & Zhou, L. (2021). Tuberculosis-related stigma and its determinants in Dalian, Northeast China: a cross-sectional study. BMC Public Health, 21(1), 1–10. https://doi.org/10.1186/s12889-020-10055-2
Dewi, B. A. S., Sari, I. R. P., Agustina, D., & Sari, S. A. (2022). Kecemasan pada Penderita Tuberculosis. Jurnal Kesehatan, 11(2), 174–177. https://doi.org/10.46815/jk.v11i2.108
Dinkes Kota Semarang. (2022). Profil Kesehatan Kota Semarang 2022. Dinas Kesehatan Kota Semarang, 6(1), 1–6.
Fuady, A., Arifin, B., Yunita, F., Rauf, S., Fitriangga, A., Sugiharto, A., Yani, F. F., Nasution, H. S., Putra, I. W. G. A. E., Mansyur, M., & Wingfield, T. (2024). Stigma, depression, quality of life, and the need for psychosocial support among people with tuberculosis in Indonesia: A multi-site cross-sectional study. PLOS Global Public Health, 4(1), 1–20. https://doi.org/10.1371/journal.pgph.0002489
Hidayat, U., Hidayat, N., Rehman, S., & Ullah, Z. (2022). Emotional Distress, Resilience and Mental Well-being among TB Patients in Peshawar. Pakistan Journal of Chest Medicine, 28(1), 38–44.
Irawan, R., Sawitri, H., & Herlina, N. (2024). Gambaran Tingkat Kecemasan pada Pasien TB Paru di Rumah Sakit Umum Cut Meutia Aceh Utara. GALENICAL : Jurnal Kedokteran Dan Kesehatan Mahasiswa Malikussaleh, 3(1), 15. https://doi.org/10.29103/jkkmm.v3i1.13022
Jones-Patten, A., Wang, Q., Molebatsi, K., Novotny, T. E., Siddiqi, K., Modongo, C., Zetola, N. M., Mbongwe, B., & Shin, S. S. (2023). Depression, Anxiety, and Cigarette Smoking Among Patients with Tuberculosis. Clinical Nursing Research, 32(1), 22–28. https://doi.org/10.1177/10547738221132096
Kementerian Kesehatan Republik Indonesia. (2023). Revisi Strategi Nasional Penanggulangan Tuberkulosis Di Indonesia 2020-2024 Dan Rencana Interim 2025-2026. 286.
Kementrian Kesehatan. (2016). Profil Kesehatan Indonesia 2023.
Khoerunisa, E. F., Setiawan, A., Tarjuman, T., & Fathudin, Y. (2023). Lama Pengobatan terhadap Tingkat Kecemasan Pasien TB Paru di Poli Paru RSUD Al - Ihsan Provinsi Jawa Barat. Jurnal Keperawatan Indonesia Florence Nightingale, 3(1), 44–51. https://doi.org/10.34011/jkifn.v3i1.1362
Lara-Espinosa, J. V., & Hernández-Pando, R. (2021). Psychiatric Problems in Pulmonary Tuberculosis: Depression and Anxiety. Journal of Tuberculosis Research, 09(01), 31–50. https://doi.org/10.4236/jtr.2021.91003
Liu, X., Qiu, X., Lan, H., Diao, L. Y., Huang, W., Wen, Y., Feng, M., & Tang, X. (2024). Symptom network analysis of insomnia-depression-anxiety-stigma in tuberculosis patients. Frontiers in Psychiatry, 15(January), 1–10. https://doi.org/10.3389/fpsyt.2024.1513524
Mohammedhussein, M., Dule, A., Tessema, W., Mamaru, A., & Alenko, A. (2023). Perceived stress and its psychosocial and clinical correlates among patients with pulmonary tuberculosis: A cross-sectional study. Indian Journal of Psychiatry, 65(1), 103–106. https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_1356_20
Moscibrodzki, P., Enane, L. A., Hoddinott, G., Brooks, M. B., Byron, V., Furin, J., Seddon, J. A., Meyersohn, L., & Chiang, S. S. (2021). The impact of tuberculosis on the well-being of adolescents and young adults. Pathogens, 10(12), 1–17. https://doi.org/10.3390/pathogens10121591
Panati, D., Chittooru, C. S., Madarapu, Y. R., & Gorantla, A. K. (2023). Effect of depression on treatment adherence among elderly tuberculosis patients: A prospective interventional study. Clinical Epidemiology and Global Health, 22(June), 101338. https://doi.org/10.1016/j.cegh.2023.101338
Rahma, G., Hasnah, F., & Alhamda, S. (n.d.). Determinan Kesehatan Mental Pada Remaja Usia 11-18 Tahun di Kota Padang Determinants of Mental Health in Adolescents Aged 11-18 Years in Padang. 8(2).
Stanikzai, M. H., Rahimy, N., Baray, A. H., Anwary, Z., Ahmad, M., & Sayam, H. (2024). High stigma prevalence and associated factors among TB patients in Southern Afghanistan: A multi-center cross-sectional study. Indian Journal of Tuberculosis, 71(May), 6–10. https://doi.org/10.1016/j.ijtb.2024.08.005
Vanteemar S. Sreeraj, S., Uvais2, N. A., Mohanty3, S., Kumar3, S., & Department. (2019). Indian nursing students’ attitudes toward mental illness and persons with mental illness. Industrial Psychiatry Journal, 195–201. https://doi.org/10.4103/ipj.ipj
Wingfield, T., Fuady, A., Anindhita, M., Haniifah, M., Putri, A., Karnasih, A., Agiananda, F., Yani, F., Haya, M., & Pakasi, T. (2024). Codeveloping a community-based, peer-led psychosocial support intervention to reduce tuberculosis-related stigma in Indonesia: a mixed-methods participatory action study. https://doi.org/10.1038/s41533-024-00407-5
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