Geographical Variations in Moringa Oleifera and Its Potential for Stunting Intervention: A Systematic Review

  • Ika Muryasari Poltekkes Kemenkes Semarang
  • Melyana Nurul Widyawati Poltekkes Kemenkes Semarang
  • Kurnianingsih Kurnianingsih Politeknik Negeri Semarang
  • Nita Aquarista Poltekkes Kemenkes Semarang
Keywords: height, moringa leaf extract, nutritional compounds, stunting, weight

Abstract

Stunting is a major global health issue, particularly in Indonesia, where malnutrition rates remain high. Poor childhood nutrition affects growth, cognition, and long-term health. Moringa oleifera is a nutrient-rich herbal supplement, but its nutritional composition varies by geography, potentially influencing its effectiveness in stunting interventions. Objective: To identify the best Moringa leaf source for extract production to support weight and height improvement in stunted children. Method: A systematic literature review (SLR) was conducted using Google Scholar, ScienceDirect, and PubMed (2014–2024). From 70 initially identified articles, 6 were selected using the PICOS method, focusing on Moringa supplementation, malnourished children, and growth outcomes. Results: Highland Moringa contains higher vitamin C and flavonoid levels, while lowland Moringa offers greater biomass for large-scale production. Studies confirm that dried Moringa extract significantly improves weight gain (p = 0.002), though its effects on height and inflammation reduction were less pronounced. Conclusion: Dried Moringa extract shows promise for weight gain and nutrition enhancement in stunted children. However, geographical factors influence its nutrient content, requiring further research to standardize formulations, optimize dosages, and assess long-term effects in human trials.

References

Addae, H., Sulemana, M., Yakubu, T., Atosona, A., Tahiru, R., & Azupogo, F. (2024). Low birth weight, household socio-economic status, water and sanitation are associated with stunting and wasting among children aged 6–23 months: Results from a national survey in Ghana. PLoS ONE, 19(3).

Aquarista, N. (2024). Efektivitas pemberian ekstrak daun kelor dengan sistem ekstraksi otomatis terhadap kadar il-6 pada tikus model kurang energi protein (kep) [Poltekkes Kemenkes Semarang]. https://repository.poltekkes-smg.ac.id/index.php?p=show_detail&id=41624&keywords=aquarista

Badan Kebijakan Pembangunan Nasional. (2023). Survei Kesehtan Nasional.

Depkes RI. (2018). Riset Kesehatan Dasar (RISKESDAS) 2018.

Indonesia KKR. (2021). Buku Saku Kader Pintar Cegah Stunting (Kementerian Kesehatan Republik Indonesia (ed.)). Kementerian Kesehatan Republik Indonesia.

Karlsson, O., Kim, R., & Bogin, B. (2022). Maternal height-standardized prevalence of stunting in 67 low-and middle-income countries. Journal of Epidemiology, 32(7), 337–344.

Kashyap, P., Kumar, S., Riar, C. S., Jindal, N., Baniwal, P., Guiné, R. P. F., Correia, P. M. R., Mehra, R., & Kumar, H. (2022). Recent Advances in Drumstick (Moringa oleifera) Leaves Bioactive Compounds: Composition, Health Benefits, Bioaccessibility, and Dietary Applications. Antioxidants, 11(2), 1–37. https://doi.org/10.3390/antiox11020402

Kemenkes RI. (2018). Buletin Stunting.

Kemenkes RI. (2023). Buku Saku Hasil Survei Status Gizi Indonesia (SSGI) 2022. In Kemenkes. https://kesmas.kemkes.go.id/assets/uploads/contents/attachments/09fb5b8ccfdf088080f2521ff0b4374f.pdf

Kurnianingsih, Suharjono, A., Suryono, Widyowati, R., & Kubota, N. (2021). Optimization of Moringa Leaf Extraction and Time Series-based Forecasting for an Early Warning System during Extraction. 2021 IEEE Region 10 Symposium (TENSYMP), 1–6. https://doi.org/10.1109/TENSYMP52854.2021.9550816

Kurnianingsih, Widyowati, R., Aji, A. F., Widyawati, M. N., Aquarista, N., & Arianto, H. T. (2023). Kelor Super: Ekstraksi, Pengujian, dan Manfaatnya untuk Stunting (1st ed.). PT. Manggala Jaya Technology.

Leone, A., Spada, A., Batterzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2016). Moringa oleifera seeds and oil: Characteristics and uses for human health. International Journal of Molecular Sciences, 17(12), 21–41.

Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015). Cultivation , Genetic , Ethnopharmacology , Phytochemistry and Pharmacology of Moringa oleifera Leaves : An Overview. International Journal of Molecular Sciences, 16, 12791–12835. https://doi.org/10.3390/ijms160612791

Luetragoon, T., Sranujit, R. P., Noysang, C., Thongsri, Y., Potup, P., Suphrom, N., Nuengchamnong, N., & Usuwanthim, K. (2020). Bioactive compounds in moringa oleifera Lam. Leaves inhibit the pro-inflammatory mediators in lipopolysaccharide-induced human monocyte-derived macrophages. Molecules, 25(1), 1–16. https://doi.org/10.3390/molecules25010191

Masitlha, E., Seifu, E., & Teketay, D. (2024). Nutritional composition and mineral profile of leaves of Moringa oleifera provenances grown in Gaborone, Botswana. Food Product Process and Nutrition, 6(2). https://doi.org/10.1186/s43014-023-00183-8

Patil, S., Mohite, B., Marathe, K., & Salunkhe, N. (2022). Moringa tree, gift of nature: a review on nutritional and industrial potential. Current Pharmacology Reports, 8(4), 262–280.

Pitoyo, A., Saputri, A., Agustina, R., & Handayani, T. (2022). Analysis of determinan of stunting prevalence among stunted toddlers in Indonesia. Populasi, 30(1), 36.

Pratiwi, A., Nofita, & Winahyu, D. (2021). Perbandingan kadar besi (fe) pada daun kelor (moringa oleiera) yang tumbuh di dataran tinggi dan dataran rendah secara spektrofotometri serapan atom (ssa). Jurnal Analis Farmasi, 6(2), 102–108. https://doi.org/10.33024/jaf.v6i2.5945

Ramesh M, E. S. (2019). Moringa (Moringa oleifera Lam.): A Review. International Journal of Homeopathic Sciences, 3(4), 37–40. https://doi.org/https://doi.org/:10.17660/ActaHortic.2011.911.58

Saputri, A., Purwanti, R., & Christiandari, H. (2022). Perbandingan kadar vitamin c pada daun kelor (moringa oleifera) yang tumbuh di datararan rendah, dataran rendah menengah dan dataran tinggi. Jurnal Permata Indonesia, 13(1), 62–67. https://doi.org/10.59737/jpi.v13i1.46

Sawadogo-Lewis, T., King, S., Agung, T., & Roberton, T. (2021). The potential contribution of the health system to reducing stunting in SUN countries. Food and Nutrition Bulltetin, 42(2), 159–169.

Tawfik, M., Mohammed, M., Sadak, M., & Thalooth, A. (2021). Iron oxide nanoparticles effect on growth, physiological traits and nutritional contents of Moringa oleifera grown in saline environment. Bulletin of National Research Centre, 49(2021), 1–9.

UNICEF Indonesia. (2022). Laporan Tahunan UNICEF Indonesia 2022. In UNICEF Laporan Tahunan Indonesia 2022.

WHO. (2020). Global Nutrition Report: Action on Equity to End Malnutrition.

World Health Organization. (2025). Global Targets 2025: To improve maternal, infant and young child nutrition. Nutrition and Food Safety. https://www.who.int/teams/nutrition-and-food-safety/global-targets-2025

Yajie, C., Shiguan, F., & Jiashun, G. (2016). A comparative study of components of moringa oleifera leaves form different regions in Yunnan. Journal of Food Science, 2, 160–164. https://doi.org/Doi:10.7506/spkx1002-6630-201602028

Published
2025-03-17
How to Cite
Muryasari, I., Widyawati, M. N., Kurnianingsih, K., & Aquarista, N. (2025). Geographical Variations in Moringa Oleifera and Its Potential for Stunting Intervention: A Systematic Review. Indonesian Journal of Global Health Research, 7(3), 75-82. https://doi.org/10.37287/ijghr.v7i3.5787