Evaluation of Antibiotic use with the ATC/DDD Method and DU 90% on Respiratory Tract Infection Patients
Abstract
Drug availability is one of the factors in the success of pharmaceutical services at the community health center (Puskesmas) as a Primary Health Facility (FKTP). The aim of this study was to determine the quantity of antibiotic use using the ATC/DDD method and DU 90%, as well as the percentage of antibiotic prescription conformity with the National Formulary (Fornas). The method used was an observational cross-sectional study with a descriptive approach. Data were collected retrospectively for the period of May to October 2024 at Khomba Health Center, Jayapura Regency. The results of this study indicate that the most commonly used antibiotic was Amoxicillin with a value of (1996.36 DDD/1,000/year). The antibiotic included in the DU 90% segment was Amoxicillin, and the level of prescription conformity with the National Formulary (Fornas) reached 100%.
References
American Diabetes Association (ADA). (2023). American Diabetes Association Standards of Care in Diabetesd 2023. American Diabetes Association, 46(January), 64–64. https://doi.org/10.1057/978-1-349-96073-6_16356
Chen, Y., Williams, E., & Kirk, M. (2014). Risk factors for acute respiratory infection in the Australian community. PLoS ONE, 9(7). https://doi.org/10.1371/journal.pone.0101440
Dewi, R., Dewi, R., Sutrisno, D., Sutrisno, D., & Medina, F. (2020). Evaluasi Penggunaan Antibiotik Infeksi Saluran Pernapasan Atas pada Anak di Puskesmas Olak Kemang Kota Jambi Tahun 2018. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 17(1), 158. https://doi.org/10.30595/pharmacy.v17i1.6936
Dinas Kesehatan Kabupaten Jayapura. (2021). Profil Kesehatan Kabupaten Jayapura Tahun 2020.
Ekasari, D. P., & Hastuti, D. (2022). Rasionalitas Peresepan Antibiotika Pada Pasien di Klinik Telkomedika Health Center Yogyakarta. Jurnal Kesehatan Tambusai, 3(1), 217–225. https://scholar.archive.org/work/dgbawd6pozfunhums23gret3cy/access/wayback/http://journal.universitaspahlawan.ac.id/index.php/jkt/article/download/3993/2610
Falagas, M. E., Mourtzoukou, E. G., & Vardakas, K. Z. (2007). Sex differences in the incidence and severity of respiratory tract infections. Respiratory Medicine, 101(9), 1845–1863. https://doi.org/10.1016/j.rmed.2007.04.011
Falevi, R. (2022). Evaluasi ketepatan Penggunaan Antibiotik pada Pasien Infeksi Saluran Pernafasan Akut Atas di Puskesmas Junrejo Kota Batu Tahun 2020.
Heta, S., & Robo, I. (2018). The Side Effects of the Most Commonly Used Group of Antibiotics in Periodontal Treatments. Medical Sciences (Basel, Switzerland), 6(1), 1–6. https://doi.org/10.3390/medsci6010006
Ihsan, S., & Akib, N. (2016). Studi Penggunaan Antibiotik Non Resep Di Apotek Komunitas Kota Kendari Study Of Non Prescription Use Of Antibiotics On Community Pharmacy In Kendari. Media Farmasi, 13(2), 272–284.
Ihsan, S., Sabarudin, S., Nuralifah, N., Kasmawati, H., Leorita, M., Damu, R., Sudiman, A., Jamsir, A., Hasniar, W. O., Septiyana, W., Mardiani, S., Ariani, E. R., & Ningsih, W. A. (2020). Evaluasi Penggunaan Antibiotik pada Pasien Pediatrik ISPA Non Pneumonia Menggunakan Sistem ATC/DDD di Seluruh Puskesmas Kota Kendari. Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan, 5(2), 1–6. https://doi.org/10.33772/pharmauho.v5i2.10166
Kemenkes RI. (2017). Petunjuk Teknis Evaluasi Penggunaan Obat di Fasilitas Kesehatan. Jakarta: Kementerian Kesehatan Republik Indonesia.
Khairinnisa, A., Yusmaini, H., & Hadiwiardjo, Y. H. (2020). Perbandingan Penggunaan Glibenclamid-Metformin dan Glimepirid-Metformin Terhadap Efek Samping Hipoglikemia Pasien Diabetes Melitus Tipe-2 di Kota Tangerang Selatan Bulan Januari–Oktober Tahun 2019. Seminar Nasional Riset Kedokteran,Jakarta. Di Dalam: Seminar Nasional Riset Kedokteran (SENSORIK) 2020, Program Studi Sarjana Kedokteran, Fakultas Kedokteran Universitas Pembangunan Nasional., 4(2), 147–154.
Kon, K., & Rai, M. (2016). Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches. In Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches. https://doi.org/10.1016/C2015-0-00104-6
Maidi, M., Dewi, C., & Idrus, M. (2024). Evaluasi Penggunaan Antibiotik Pada Pasien Infeksi Saluran Pernapasan Atas ( ISPA ) dengan Metode Gyssens di Puskesmas Tanjung Harapan Kecamatan Menui Kepulauan Kabupaten Morowali Periode Januari – Juni 2022 Evaluation of The Use of Antibiotics in Patient. 3(5).
Mugopal, R. I., Dewi, A. M. K., Hardaningsih, G., & Nugroho, T. W. (2021). the Difference of Risk Factors of Acute Upper Respiratory Tract Infection in the Urban and Rural Public Health Center Semarang. Diponegoro Medical Journal (Jurnal Kedokteran Diponegoro), 10(3), 183–188. https://doi.org/10.14710/dmj.v10i3.29989
Ningrum, S. S., & Gunawan, S. (2023). Gambaran Ketepatan Penggunaan Antibiotik pada Kasus Infeksi Saluran Pernafasan Akut di Poli Anak RSUD Batara Siang, Sulawesi Selatan. 5, 3253–3265.
Reichert, V. C., Seltzer, V., Efferen, L. S., & Kohn, N. (2009). Women and Tobacco Dependence. Obstetrics and Gynecology Clinics of North America, 36(4), 877–890. https://doi.org/10.1016/j.ogc.2009.10.003
Riska Aulia, I. C. (2017). Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Di Rumah Sakit Pku Muhammadiyah Bantul. Jurnal Pharmacy, 14(juli), 1–10.
Riskesdas. (2018). Hasil Utama Riset Kesehata Dasar (RISKESDAS). [Internet]. Jakarta: Kementerian Kesehatan Republik Indonesia Badan Penelitian Dan Pengembangan Kesehatan. https://doi.org/10.1088/1751-8113/44/8/085201
Salsabila, L., Suri, N., & Adjeng, A. N. T. (2024). Potensi Interaksi Obat Pada Pasien Pneumonia. Jurnal Farmasi Higea, 16(1), 95. https://doi.org/10.52689/higea.v16i1.503
Seppala H. et al. (1997). the Effect of Changes in the Consumption of Macrolide. The New England Journal of Medicine, 337(7), 441–446.
Sitepu, R., Cahyono, T. T., & Monica, E. (2020). Evaluasi Penggunaan Antibiotik Dengan Metode Atc/Ddd Dan Pdd Dengan Du 90% Pada Penderita Ispa Non Pneumonia Di Puskesmas Kabupaten Sampang. Jurnal JKFT, 5(1), 16. https://doi.org/10.31000/jkft.v1i1.2664
Sugiharta, S. (2018). Evaluasi Penggunaan Antibiotik Pada Pasien Balita Dengan Diagnosa Ispa Bukan Pneumonia Di Puskesmas Bogor Timur. Jurnal Inkofar, 1(1), 91–100. https://doi.org/10.46846/jurnalinkofar.v1i1.64
Tamayo, E., Montes, M., Vicente, D., & Pérez-Trallero, E. (2016). Streptococcus pyogenes pneumonia in adults: Clinical presentation and molecular characterization of isolates 2006-2015. PLoS ONE, 11(3). https://doi.org/10.1371/journal.pone.0152640
Tuloli, T. S., Akuba, J., Djuwarno, E. N., Makkulawu, A., & Ahmad, R. A. (2024). Profil Penggunaan Obat Antibiotik pada Penderita Infeksi Saluran Pernapasan Akut (ISPA) di Puskesmas Kabupaten Gorontalo. Journal Syifa Sciences and Clinical Research, 6(1), 9–19. https://doi.org/10.37311/jsscr.v6i1.21889
Wasilah, T., Dewi, R., & Sutrisno, D. (2022). Evaluasi Kerasionalan Penggunaan Obat Antihipertensi Pada. 2(1), 21–31. https://doi.org/10.37311/ijpe.v2i1.13788
Winda, S. W. (2018). Formularium Nasional (FORNAS) dan e-Catalogue Obat Sebagai Upaya Pencegahan Korupsi dalam Tata Kelola Obat Jaminan Kesehatan Nasional (JKN). Integritas, 4(2), 177–206. https://doi.org/10.32697/integritas.v4i2.328
World Health Organization. (2020). Pusat Pengobatan Infeksi Saluran Pernapasan Akut Berat. World Health Organization, 100. (WHO/2019-nCoV/SARI_treatment_center / 2020.1)
Wulandari, Y., Padmasari, S., & Larasati, N. (2021). Evaluasi Rasionalitas Penggunaan Obat Antidiabetik pada Pasien Diabetes melitus Tipe 2 Rawat Jalan. 2–3.
Zaini, M., Muliyani, M., Soediono, J. B., & Destiana, E. (2019). Pola Persepan Antibiotik Pada Pasien Pneumonia Di Poli Anak Rsud Dr. H. M. Ansari Saleh Banjarmasin Tahun 2017. Jurnal Insan Farmasi Indonesia, 2(1), 138–148. https://doi.org/10.36387/jifi.v2i1.306.
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