Comparison of Plating Versus Intramedullary Nailing in Metaphyseal Fractures: A Systematic Review and Meta-Analysis
Abstract
Metaphyseal fractures are common orthopedic injuries that often require surgical intervention for optimal management. The choice between plating and intramedullary nailing as fixation methods remains a subject of debate among orthopedic surgeons, with considerations including fracture type, patient characteristics, and surgical outcomes. This study aim to compare the efficacy, safety, and outcomes of plating versus intramedullary nailing in the treatment of metaphyseal fractures.Methods: A comprehensive search was conducted across major electronic databases for relevant studies published up to 2023. Studies comparing plating and nailing techniques in metaphyseal fracture fixation were included. Data regarding study characteristics, patient demographics, surgical techniques, outcomes, and follow-up durations were extracted and analyzed using appropriate statistical methods. Our primary outcomes were union rate and time, functional outcome using patient reported outcome measure, and complications. Results: The initial search yielded a total of 687 studies, of which 7 studies met the inclusion criteria, consisting of a total of 758 skeletally-mature patients with metaphyseal fractures treated with either intramedullary nailing or plate fixations. The meta-analysis revealed that there is no evidence to draw definitive conclusions on which indicates the best method in treating metaphyseal fractures. Subgroup analyses were performed based on fracture type, patient age, and other relevant factors to further elucidate the comparative effectiveness of plating versus screwing.Conclusion: The meta-analysis findings indicated that using intramedullary nailing led to shorter surgical and complications when compared to plate fixation. Additionally, both treatments frequently resulted in similar union times and union-related issues. However, further randomized controlled trials (RCTs) are necessary to bolster the existing evidence base.
References
Borrelli, J., Prickett, W., Song, E., Becker, D., & Ricci, W. (2002). Extraosseous Blood Supply of the Tibia and the Effects of Different Plating Techniques: A Human Cadaveric Study. J Orthop Trauma, 16(10), 691–695. http://journals.lww.com/00005131-200211000-00002
Chen, F., Huang, X., Ya, Y., Ma, F., Qian, Z., & Shi, J. (2018). Finite element analysis of intramedullary nailing and double locking plate for treating extra-articular proximal tibial fractures. J Orthop Surg Res, 13(1), 12. https://josr-online.biomedcentral.com/articles/10.1186/s13018-017-0707-8
Chun, D., Min, T.-H., Kang, E. M., Yu, W., Won, S. H., Cho, J., & Yi, Y. (2022). Comparison of Radiological and Clinical Outcomes in Patients Treated with Standard Plating versus Intramedullary Nailing in Distal Tibial Fracture. Orthopaedic Surgery, 14(3), 536–542. https://doi.org/10.1111/os.13210
Cochrane. (2022). Risk of Bias 2 Cochrane Review Group Starter Pack.
Costa, M. L., Achten, J., Griffin, J., Petrou, S., Pallister, I., & Lamb, S. E. (2017). Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia. JAMA, 318(18), 1767. http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.2017.16429
Fang, J. H., Wu, Y. S., Guo, X. S., & Sun, L. J. (2016). Comparison of 3 Minimally Invasive Methods for Distal Tibia Fractures. Orthopedics, 39(4). https://journals.healio.com/doi/10.3928/01477447-20160606-01
Filardi, V. (2015). The healing stages of an intramedullary implanted tibia: A stress strain comparative analysis of the calcification process. J Orthop, 51–61. https://linkinghub.elsevier.com/retrieve/pii/S0972978X15000173
Francois, J., Vandeputte, G., Verheyden, F., & Nelen, G. (2004). Percutaneous plate fixation of fractures of the distal tibia. Acta Orthop Belg, 70(2), 148–154. http://www.ncbi.nlm.nih.gov/pubmed/15165017
Guo, C., Ma, J., Ma, X., Wang, Y., Sun, L., & Lu, B. (2018). Comparing intramedullary nailing and plate fixation for treating distal tibail fractures: A meta-analysis of randomized controlled trials. International Journal of Surgery, 5–11. https://linkinghub.elsevier.com/retrieve/pii/S1743919118306241
Hartono, F., Ananditya, T., Augustinus, Y., Nicholas, H., & Significances, S. (2024). Metaphyseal trauma of the lower extremities in major orthopedic surgery as an independent risk factor for deep vein thrombosis American Academy of Orthopaedic Surgeon American College of Chest Physicians. European Journal of Orthopaedic Surgery & Traumatology, 34(5), 2797–2803. https://doi.org/10.1007/s00590-024-03960-4
Hu, L., Xiong, Y., Mi, B., Panayi, A. C., Zhou, W., & Liu, Y. (2019). Comparison of intramedullary nailing and plate fixation in distal tibial fractures with metaphyseal damage: a meta-analysis of randomized controlled trials. J Orthop Surg Res, 14(1), 30. https://josr-online.biomedcentral.com/articles/10.1186/s13018-018-1037-1
Iqbal, H. J., & Pidikiti, P. (2013). Treatment of distal tibia metaphyseal fractures; plating versus intramedullary nailing: A systematic review of recent evidence. Foot and Ankle Surgery, 19(3), 143–147. https://linkinghub.elsevier.com/retrieve/pii/S1268773113000507
Lefaivre, K. A., Guy, P., Chan, H., & Blachut, P. A. (2008). Long-Term Follow-up of Tibial Shaft Fractures Treated With Intramedullary Nailing. J Orthop Trauma, 8, 525–529. https://journals.lww.com/00005131-200809000-00004
Li, Y., Jiang, X., Guo, Q., Zhu, L., Ye, T., & Chen, A. (2014). Treatment of distal tibial shaft fractures by three different surgical methods: a randomized, prospective study. Int Orthop, 38(6), 1261–1267. http://link.springer.com/10.1007/s00264-014-2294-1
Mao, Z., Wang, G., Zhang, L., Zhang, L., Chen, S., & Du, H. (2015). Intramedullary nailing versus plating for distal tibia fractures without articular involvement: a meta-analysis. J Orthop Surg Res, 10(1), 95. https://josr-online.biomedcentral.com/articles/10.1186/s13018-015-0217-5
Mauffrey, C., McGuinness, K., Parsons, N., Achten, J., & Costa, M. L. (2012). A randomised pilot trial of “locking plate” fixation versus intramedullary nailing for extra-articular fractures of the distal tibia. J Bone Joint Surg Br, 94(5), 704–708. https://online.boneandjoint.org.uk/doi/10.1302/0301-620X.94B5.28498
O’TOOLE, M. (1946). Fracture of shaft of the femur treated with Küntscher intramedullary nail. Nurs Times, 42(34), 640. http://www.ncbi.nlm.nih.gov/pubmed/20999215
Ocalan, E., Ustun, C. C., & Aktuglu, K. (2019). Locking plate fixation versus antegrade intramedullary nailing for the treatment of extra-articular distal femoral fractures. Injury, 55–62. https://linkinghub.elsevier.com/retrieve/pii/S0020138319304073
Page, M. J., Moher, D., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., Mcdonald, S., … Mckenzie, J. E. (2021). PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews. The BMJ, 372. https://doi.org/10.1136/bmj.n160
Polat, A., Kose, O., Canbora, K., Yanık, S., & Guler, F. (2015). Intramedullary nailing versus minimally invasive plate osteosynthesis for distal extra-articular tibial fractures: a prospective randomized clinical trial. Journal of Orthopaedic Science, 20(4), 695–701. https://linkinghub.elsevier.com/retrieve/pii/S0949265815300464
Shen, J., Xu, J., Jie, T. M., Feng, L. C., & Qing, Z. C. (2016). Extra-articular distal tibia facture (AO-43A): A retrospective study comparing modified MIPPO with IMN. Injury, 47(10), 2352–2359. https://linkinghub.elsevier.com/retrieve/pii/S0020138316303011
Wani, I. H., Gani, N., Yaseen, M., Bashir, A., Bhat, M. S., & Farooq, M. (2017). Operative Management of Distal Tibial Extra-articular Fractures – Intramedullary Nail Versus Minimally Invasive Percutaneous Plate Osteosynthesis. Ortop Traumatol Rehabil, 19(6), 537–541. https://ortopedia.com.pl/gicid/01.3001.0010.8045
Yang, S. W., Tzeng, H. M., Chou, Y. J., Teng, H. P., Liu, H. H., & Wong, C. Y. (2006). Treatment of distal tibial metaphyseal fractures: Plating versus shortened intramedullary nailing. Injury, 37(6), 531–535. https://linkinghub.elsevier.com/retrieve/pii/S0020138305003839
Yao, Q., Ni, J., Bin, P. L., Xin, Y. D., & Ming, Y. X. (2013). Locked plating with minimally invasive percutaneous plate osteosynthesis versus intramedullary nailing of distal extra-articular tibial fracture: a retrospective study. Zhonghua Yi Xue Za Zhi, 93(47), 3748–3751. http://www.ncbi.nlm.nih.gov/pubmed/24548389
Zha, G., Chen, Z., & Qi, X. (2008). Minimally invasive percutaneous locking compression plate internal fixation in the treatment of tibial fractures. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 22(12), 1448–1450. http://www.ncbi.nlm.nih.gov/pubmed/19137887
Copyright (c) 2025 Indonesian Journal of Global Health Research

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.