Experiences of Breast Cancer Patients with Acute Skin Toxicity Undergoing Radiotherapy
Abstract
Radiotherapy for breast cancer has been proven to be highly effective, able to significantly reduce the risk of recurrence and lower the risk of death in the long term. However, behind these great benefits, there are side effects that need to be considered, such as skin toxicity, which can have a significant impact on the patient's physical and psychological condition. Therefore, it is necessary to review various literature to determine the various experiences of breast cancer patients with acute skin toxicity who underwent radiotherapy. Objective: To explore and analyze the experiences of breast cancer patients with acute toxicity undergoing radiotherapy through the literature. Method: Search for articles using the keywords acute skin toxicity AND breast cancer AND experience AND radiotherapy. Articles were searched through three online databases, namely sciencedirect (n = 43 articles), pubmed (n = 38 articles), and proquest (n = 32 articles). A total of 113 articles were collected through the data base. Through three screening processes that met the criteria, 4 articles were obtained. Results: This study found an outline of the classification of themes that emerged, namely: physical, functional, psychological impacts, and prevention of skin disorders due to radiotherapy as well as knowledge of breast cancer patients regarding radiotherapy. It is hoped that the results of this research can contribute to improving health care by expanding the scope of services to not only cover physical problems but also non-physical.
References
Acosta, L. G., Takita, C., Reis, I. M., Wright, J. L., Zhao, W., & Hu, J. J. (2023). Abstract 3052: Patient- and clinician-reported outcomes of radiotherapy-related acute skin toxicities in a tri-racial/ethnic breast cancer population. Cancer Research, 83(7_Supplement), 3052. https://doi.org/10.1158/1538-7445.AM2023-3052
American Cancer Society. (2019). Breast Cancer Facts & Figures 2019-2020.
Andersen, E. R., Eilertsen, G., Myklebust, A. M., & Eriksen, S. (2018). Women’s experience of acute skin toxicity following radiation therapy in breast cancer. Journal of Multidisciplinary Healthcare, 11, 139–148. https://doi.org/10.2147/JMDH.S155538
Astari, A. M., Hayati, Y. S., AR, D. I. P., & Laksana, K. (2023). The Experience of Breast Cancer Undergoing Chemotherapy. Jurnal Aisyah : Jurnal Ilmu Kesehatan, 8(2), 21–26. https://doi.org/10.30604/jika.v8i2.1528
Beamer, L. C., & Grant, M. (2018). Longitudinal trends in skin-related and global quality of life among women with breast radiodermatitis: A pilot study. European Journal of Oncology Nursing, 33(December 2017), 22–27. https://doi.org/10.1016/j.ejon.2018.01.008
Beamer, L. C., & Grant, M. (2019). Skin-related quality of life among Midwestern US Community-based women with breast cancer experiencing radiodermatitis. Asia-Pacific Journal of Oncology Nursing, 6(1), 50–56. https://doi.org/10.4103/apjon.apjon_40_18
Bruand, M., Salleron, J., Guihard, S., Crety, C. M., Liem, X., Pasquier, D., Lamrani-Ghaouti, A., Charra-Brunaud, C., Peiffert, D., Clavier, J. B., Desandes, E., & Faivre, J. C. (2022). Acute skin toxicity of conventional fractionated versus hypofractionated radiotherapy in breast cancer patients receiving regional node irradiation: the real-life prospective multicenter HYPOBREAST cohort. BMC Cancer, 22(1), 1–10. https://doi.org/10.1186/s12885-022-10402-z
Cardozo, A. D. S., Simões, F. V., Santos, V. O., Portela, L. F., & da Silva, R. C. (2020). Severe radiodermatitis and risk factors associated in head and neck cancer patients. Texto e Contexto Enfermagem, 29, 1–15. https://doi.org/10.1590/1980-265X-TCE-2018-0343
Chitapanarux, I., Nobnop, W., Onchan, W., Klunklin, P., Nanna, T., Sitathanee, C., Kulpisitthicharoen, S., & Sripan, P. (2023). Hypofractionated whole breast irradiation with simultaneous integrated boost in breast cancer using helical tomotherapy with or without regional nodal irradiation: A report of acute toxicities. Frontiers in Oncology, 13(March), 1–7. https://doi.org/10.3389/fonc.2023.1122093
Chu, C. N., Hu, K. C., Wu, R. S. C., & Bau, D. T. (2021). Radiation-irritated skin and hyperpigmentation may impact the quality of life of breast cancer patients after whole breast radiotherapy. BMC Cancer, 21(1), 1–8. https://doi.org/10.1186/s12885-021-08047-5
Critical Appraisal Skills Programme. (2018). CASP Qualitative Checklist. Critical Appraisal Skills Programe, 2018, 1.
Early Breast Cancer Trialists’ Collaborative Group. (2011). Relevance of breast cancer hormone receptors and other factors to the effi cacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Comprehensive Cancer CentreHealth Service & Population Research, 378(9793), 771–784.
Esteban-Zubero, E., García-Muro, C., Alatorre-Jiménez, M. A., Marín-Medina, A., López-García, C. A., Youssef, A., & Villeda-González, R. (2019). Management of Community acquired pneumonia in the Emergency Room. Iberoamerican Journal of Medicine, 1(1), 3–15. https://doi.org/10.53986/ibjm.2019.0002
Fitriatuzzakiyyah, N., Sinuraya, R. K., & Puspitasari, I. M. (2017). Cancer Therapy with Radiation: The Basic Concept of Radiotherapy and Its Development in Indonesia. Indonesian Journal of Clinical Pharmacy, 6(4), 311–320. https://doi.org/10.15416/ijcp.2017.6.4.311
Fuzissaki, M. de A., Paiva, C. E., Oliveira, M. A. de, Lajolo Canto, P. P., & Paiva Maia, Y. C. de. (2019). The Impact of Radiodermatitis on Breast Cancer Patients’ Quality of Life During Radiotherapy: A Prospective Cohort Study. Journal of Pain and Symptom Management, 58(1), 92-99.e1. https://doi.org/10.1016/j.jpainsymman.2019.03.017
Ginex, P. K., Backler, C., Croson, E., Horrell, L. N., Moriarty, K. A., Maloney, C., Vrabel, M., & Morgan, R. L. (2020). Radiodermatitis in patients with cancer: Systematic review and meta-analysis. Oncology Nursing Forum, 47(6), E225–E236. https://doi.org/10.1188/20.ONF.E225-E236
İnan, G. A., Aral, I. P., Arslan, A., Celik, T. O., Ozturk, H. F., Arslan, S. A., & Tezcan, Y. (2022). Helical tomotherapy experience in breast cancer adjuvant radiotherapy and acute toxicity results. Reports of Practical Oncology and Radiotherapy, 27(6), 973–981. https://doi.org/10.5603/RPOR.a2022.0121
Jacobs, J. E. J., L’Hoyes, W., Lauwens, L., Yu, Y. L., Brusselmans, M., Weltens, C., Voigt, J. U., Wildiers, H., Neven, P., Herrmann, J., Thijs, L., Staessen, J. A., Janssens, S., & Van Aelst, L. N. L. (2023). Mortality and major adverse cardiac events in patients with breast cancer receiving radiotherapy: The first decade. Journal of the American Heart Association, 12(8). https://doi.org/10.1161/JAHA.122.027855
Khanna, N., Kumar, D., Laskar, S., & Laskar, S. (2013). Radiation dermatitis: An overview. Indian Journal of Burns, 21(1), 24. https://doi.org/10.4103/0971-653x.121877
Knobf, M. T., & Sun, Y. (2005). A longitudinal study of symptoms and self-care activities in women treated with primary radiotherapy for breast cancer. Cancer Nursing, 28(3), 210–218. https://doi.org/10.1097/00002820-200505000-00010
Lu, X., Yin, Y., Geng, W., Liu, L., Liu, F., & Zhang, Z. (2024). Acute skin toxicity and self-management ability among Chinese breast cancer radiotherapy patients: a qualitative study. Supportive Care in Cancer, 32(6), 1–11. https://doi.org/10.1007/s00520-024-08583-3
Prajogi, G. Ben, & Djakaria, M. (2010). Interupsi dalam Proses Terapi Radiasi. In Journal of the Indonesian Radiation Oncology Society (Vol. 1, Issue 1).
Roszkowska, M., & Białczyk, K. (2023). Coping Styles and Quality of Life in Breast Cancer Patients Undergoing Radiotherapy. Cancers, 15(23). https://doi.org/10.3390/cancers15235515
Ruysscher, D. K. M., & Belderbos, J. S. A. (2020). Recent advances in radiotherapy for lung cancer. Lung Cancer Therapy Annual 7, 128–137. https://doi.org/10.3109/9781841848679-13
Seité, S., Bensadoun, R. J., & Mazer, J. M. (2017). Prevention and treatment of acute and chronic radiodermatitis. Breast Cancer: Targets and Therapy, 9, 551–557. https://doi.org/10.2147/BCTT.S149752
Sjövall, K., Strömbeck, G., Löfgren, A., Bendahl, P. O., & Gunnars, B. (2010). Adjuvant radiotherapy of women with breast cancer - Information, support and side-effects. European Journal of Oncology Nursing, 14(2), 147–153. https://doi.org/10.1016/j.ejon.2009.09.002
Sutherland, A. E., Bennett, N. C., & Herst, P. M. (2017). Psychological stress affects the severity of radiation-induced acute skin reactions in breast cancer patients. European Journal of Cancer Care, 26(6), 1–8. https://doi.org/10.1111/ecc.12737
Williams, F., & Jeanetta, S. C. (2016). Lived experiences of breast cancer survivors after diagnosis, treatment and beyond: Qualitative study. Health Expectations, 19(3), 631–642. https://doi.org/10.1111/hex.12372
Xie, Y., Hu, T., Chen, R., Chang, H., Wang, Q., & Cheng, J. (2023). Predicting acute radiation dermatitis in breast cancer: a prospective cohort study. BMC Cancer, 23(1), 1–13. https://doi.org/10.1186/s12885-023-10821-6
Yadav, B. S., Dahiya, D., & Gupta, M. (2023). Abstract GS5-12: Hypofractionated Radiotherapy in patients with Breast Cancer (HRBC): Acute toxicity data of a phase III randomized study. Cancer Research, 83(5_Supplement), GS5-12-GS5-12. https://doi.org/10.1158/1538-7445.SABCS22-GS5-12
Zhang, V. Y., Takita, C., Wright, J. L., Zhao, W., Reis, I. M., Lee, E., & Hu, J. J. (2023). Abstract 1108: Comparative analysis of hypofractionated and conventional fractionated radiotherapy on acute skin toxicity in a multiracial/ethnic breast cancer population. Cancer Research, 83(7_Supplement), 1108. https://doi.org/10.1158/1538-7445.AM2023-1108.
Copyright (c) 2024 Indonesian Journal of Global Health Research
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
