The Effect of Bamboo Tali Leaf Tea on Leptin Levels in Rats Metabolic Syndrome
Keywords:
bamboo leaf tea, leptin, metabolic syndrome, obesity, wistar
Abstract
Metabolic syndrome is a threat to health problems in the world, namely a group of metabolic disorders that occur simultaneously. Obesity is a risk factor for metabolic syndrome. Fat accumulation causes insulin resistance and leptin resistance resulting in weight gain. Tali bamboo leaf tea contains a natural source of antioxidants that can increase insulin sensitivity so that it can reduce leptin levels. This study aims to determine the effect of bamboo1tali leaf tea on leptin levels in rats with metabolic syndrome. This type of research is experimental laboratoric with a Pre-Post Test with a Control Group design. Wistar male white rats, 8 weeks old, and 150 – 250 grams in weight, were fed HFHF (High Fat High Fructose) for 14 days, induced by Nicotinamide and Streptozotocin. Then, the rats were divided into 5 groups, namely negative control, positive control, and 3 treatments of tali bamboo leaf tea (300, 600, and 900 mg/200 g BW) for 28 days. Measurement of leptin levels using the ELISA method.Bamboo leaf tea had a significant effect (p <0.005) on leptin levels in rats with metabolic syndrome. The largest decrease in leptin levels occurred in the TDB3 group which was 82.8% and the lowest decrease in leptin levels occurred in the TDB1 group which was 34.8%. Bamboo leaf tea doses of 300, 600, and 900 mg/200 g BW reduced leptin levels in rats with metabolic syndrome for 28 days.
References
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Xu, Y., Zhang, M., Wu, T., Dai, S., Xu, J., & Zhou, Z. (2015). The anti-obesity effect of green tea polysaccharides, polyphenols and caffeine in rats fed with a high-fat diet. Food and Function, 6(1), 297–304. https://doi.org/10.1039/c4fo00970c
Barorah, I., & Maslikhah. (2021). Buku Ajar Gizi Dalam Kesehatan Reproduksi. PT. Nasya Expanding Management.
Cahyaningrum, A. (2015). Leptin sebagai indikator obesitas, Sandubaya Mataram. Jurnal Kesehatan Prima, I(1), 1364–1371.
Chen, F., Wang, H., Zhao, J., Yan, J., Meng, H., Zhan, H., Chen, L., & Yuan, L. (2019). Grape seed proanthocyanidin inhibits monocrotaline-induced pulmonary arterial hypertension via attenuating inflammation: in vivo and in vitro studies. Journal of Nutritional Biochemistry, 67, 72–77. https://doi.org/10.1016/j.jnutbio.2019.01.013
Feng, W., Gao, C., Bi, Y., Wu, M., Li, P., Shen, S., Chen, W., Yin, T., & Zhu, D. (2017). Randomized trial comparing the effects of gliclazide, liraglutide, and metformin on diabetes with non-alcoholic fatty liver disease. Journal of Diabetes, 9(8), 800–809. https://doi.org/10.1111/1753-0407.12555
Harahap, H., Kusdiyah, E., Mhd Usni Zamzami, H., Harahap, A. H., & Malau, M. Y. R. (2021). Efek Intermittent Fasting Tipe 5:2 Terhadap Asam Urat dan Lingkar Pinggang Individu dengan Overweight dan Obesitas. Jambi Medical and Health Sciences, 000(Special Issues), 409–417.
IDF. (2018). The IDF Consensus Worldwide Definition of The Metabolic Syndrome. In IDF Communications (Vol. 28, Issue 1). https://doi.org/10.1159/000282084
Jin, D., Xu, Y., Mei, X., Meng, Q., Gao, Y., Li, B., & Tu, Y. (2013). Antiobesity and lipid lowering effects of theaflavins on high-fat diet induced obese rats. Journal of Functional Foods, 5(3), 1142–1150. https://doi.org/10.1016/j.jff.2013.03.011
Kumar, R., Mal, K., Razaq, M. K., Magsi, M., Memon, M. K., Memon, S., Afroz, M. N., Siddiqui, H. F., & Rizwan, A. (2020). Association of Leptin With Obesity and Insulin Resistance. Cureus, 12(12), 19–22. https://doi.org/10.7759/cureus.12178
Lagawa, I. N. C., Kencana, P. K. D., & Aviantara, I. G. N. A. (2020). Pengaruh Waktu Pelayuan dan Suhu Pengeringan terhadap Karakteristik Teh Daun Bambu Tabah (Gigantochloa nigrociliata BUSE-KURZ). Jurnal BETA (Biosistem Dan Teknik Pertanian), 8(2), 223. https://doi.org/10.24843/jbeta.2020.v08.i02.p05
Made, N., Wahyuni, S., Wrasiati, L. P., & Hartiati, A. (2021). Analisis Korelasi Antara Kandungan Senyawa Bioaktif dengan Aktivitas Antioksidan pada Ekstrak Daun Bambu Duri (Bambusa blumeana). Agrointek, Jurnal Teknologi Industri Pertanian, 15(4), 1062–1070. https://doi.org/10.21107/agrointek.v15i4.9853
Nikmah, U. A., & Dany, F. (2017). Kadar Leptin sebagai Petanda Diabetes pada Individu dengan Diabetes dan Toleransi Glukosa Terganggu. Buletin Penelitian Kesehatan, 45(3), 1–6. https://doi.org/10.22435/bpk.v45i3.6508.145-152
Novitasari, A. (2015). Pengaruh Ekstrak Daun Bambu Tali (Gigantochloa apus (Schult. & Shult. f.) Kurz.) Terhadap Penurunan Kadar Asam urat Darah Mencit Jantan Balb-C (Mus musculus L.) Hiperurisemia dan Pemanfaatannya Sebagai Karya Ilmiah Populer. Digital Repository Universitas Jember, 1–56. http://repository.unej.ac.id/bitstream/handle/123456789/75992/Dian Pratiwi - 132310101064 -1.pdf?sequence=1
Patonah, Susilawati, E., & Riduan, A. (2017). Aktivitas Antiobesitas Ekstrak Daun Katuk (Sauropus androgynus L. Merr). Pharmacy, 14(1), 43. https://doi.org/10.1017/CBO9781107415324.004
Pérez-Pérez, A., Vilariño-García, T., Guadix, P., Dueñas, J. L., & Sánchez-Margalet, V. (2020). Leptin and nutrition in gestational diabetes. Nutrients, 12(7), 1–18. https://doi.org/10.3390/nu12071970
Romansyah, E., Sinthia Dewi, E., Suhairin, S., Muanah, M., & Ridho, R. (2019). Identifikasi Senyawa Kimia Daun Bambu Segar Sebagai Bahan Penetral Limbah Cair. Jurnal Agrotek Ummat, 6(2), 77. https://doi.org/10.31764/agrotek.v6i2.1219
Sigit, F. S., Tahapary, D. L., Trompet, S., Sartono, E., Willems Van Dijk, K., Rosendaal, F. R., & De Mutsert, R. (2020). The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: A cross-sectional analysis of two population-based studies. Diabetology and Metabolic Syndrome, 12(1), 1–11. https://doi.org/10.1186/s13098-019-0503-1
Sumadewi, K. T. (2017). Korelasi Antara Kadar Leptin dengan IMT, Lingkar Pinggang dan RLPP pada Orang Dewasa Obesitas Usia 19-25 Tahun di Universitas Warmadewa. WMJ (Warmadewa Medical Journal), 1(2), 71. https://doi.org/10.22225/wmj.1.2.30.71-82
Thahir, A. I. A., & Masnar, A. (2021). Obesitas Anak dan Remaja: Faktor Risiko, Pencegahan, dan Isu Terkini. Edugizi Pratama Indonesia. https://books.google.co.id/books?id=L8owEAAAQBAJ
Tong, Y., Xu, S., Huang, L., & Chen, C. (2022). Obesity and insulin resistance: Pathophysiology and treatment. Drug Discovery Today, 27(3), 822–830. https://doi.org/10.1016/j.drudis.2021.11.001
Xu, Y., Zhang, M., Wu, T., Dai, S., Xu, J., & Zhou, Z. (2015). The anti-obesity effect of green tea polysaccharides, polyphenols and caffeine in rats fed with a high-fat diet. Food and Function, 6(1), 297–304. https://doi.org/10.1039/c4fo00970c
Published
2023-05-15
How to Cite
Mujayanah, A., Sari, Y., & Listyawati, S. (2023). The Effect of Bamboo Tali Leaf Tea on Leptin Levels in Rats Metabolic Syndrome. Proceedings of the International Conference on Nursing and Health Sciences, 4(1), 83-90. https://doi.org/10.37287/picnhs.v4i1.1686
Section
Articles
