Factors Affecting Disseminated Intravascular Coagulation (DIC) in Post Partum Women: A Meta Analysis
Abstract
Disseminated intravascular coagulation (DIC) is one of the risk factors that can increase mortality with a prevalence of about 82% when bleeding occurs. Information on how influential maternal characteristics are to the incidence of DIC in postpartum mothers will be very useful in detecting and performing care, however. Indonesian researchers are still lacking in conducting studies on the impact and influence of maternal characteristics with the incidence of DIC on postpartum mothers. The purpose of this meta-analysis was to find out what factors influence the incidence of DIC in postpartum mothers. Primary data is obtained by searching several indexing including: PubMed, Science Direct, Web of Science, Springer Link and Cochrane Database. By using the search keywords "factor associated AND DIC", "characteristic AND DIC", " post partum AND DIC AND adjusted odds ratio", and "factors AND DIC AND adjusted odds ratio" . Inclusion criteria, including: Full paper article with observational study design from 2018-2023. Covid-19 infection and DIC gave Odds Ratio results (OR 2.32; 95% CI: 1.67 – 3.22; p value < 0.001). Hypertension and DIC Odds Ratio (OR 2.17; 95% CI: 0.84 – 5.58; p value < 0.11). and eclampsia and DIC give an Odds Ratio result (OR 24.64; 95% CI: 6.50– 93.39; p value < 0.001).
References
Smith, L., 2021. Disseminated Intravascular Coagulation. s.l., Seminars in Oncology Nursing,.
Sunbanu, S. E. S. A. D. I. C. S. P. K. P. P. A. D. D. S. S., 2021. Skor Awal Disseminated Intravascular Coagulation Sebagai Prediktor Kematian Pada Pasien Anak Dengan Dengue Shock Syndrome. (Doctoral dissertation, Universitas Gadjah Mada).
Sohn, C. e. a., 2017. Disseminated Intravascular Coagulation in Emergency Department Patients with Primary Postpartum Hemorrhage. Shock, 48(3), p. 329–332.
Khan, L. e. a., 2021. Blood Components Therapy as a Preventive Strategy for Coagulopathy in High-Risk Obstetric Patients in a Tertiary Centre in North India - An Interventional Study. Journal of Evidence Based Medicine and Healthcare, 8(18), p. 1190–1194.
Nowak, B. S. P. P. I. S. A. Ż. K. R. W. .. &. W. W., 2020. Clinical characteristics and short-term outcomes of patients with coronavirus disease 2019: a retrospective single-center experience of a designated hospital in Poland. Pol Arch Intern Med, pp. 130(5), 407-411.
Tang, N. L. D. W. X. &. S., 2020. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. Journal of thrombosis and haemostasis, pp. 18(4), 844-847.
Lodigiani, C. I. G. C. L. C. M. F. P. S. T. F. T., 2020. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thrombosis research, p. 191.
Helms, J. T. C. S. F. L.-L. I. O. M. D. X. .. &. M. F., 2020. High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive care medicine, pp. 46(6), 1.
Hitti, J. S. L. W. S. B. T. J. &. E. T., 2018. Contribution of hypertension to severe maternal morbidity. American journal of obstetrics and gynecology, pp. 219(4), 405-e1.
Erkılınç, S. &. E. E. G. Y., 2018. Factors contributing to adverse maternal outcomes in patients with HELLP syndrome. The Journal of Maternal-Fetal & Neonatal Medicine, pp. 31(21), 2870-2876.
Teefey, C. P. D. C. P. S. S. K. &. L. L. D., 2019. Adverse maternal outcomes differ between obese and nonobese women with severe preeclampsia. American journal of perinatology, pp. 36(01), 074-078.
Zhou, X. C. Z. L. L. Z. Y. L. W. M. Z. .. &. H. Y., 2021. Incidence and impact of disseminated intravascular coagulation in COVID-19 a systematic review and meta-analysis. Thrombosis research, pp. 201, 23-29.
Jing Lu, L. Y. G. J.-y. L. Q.-f., 2020. Clinical feature analysis on death cases of the COVID-19. Tianjin Medical Journal , p. 48 (06); 465–469.
D. Paparella, M. C. E. S. P. R. F. D. P. P. R. M. A. M. S. G., 2020. Clotting abnormalities in critically ill COVID-19 patients are inconsistent with overt disseminated intravascular coagulation. Thromb. Res, pp. 196; 272-275.
T. Iba, M. D. N. J. T. H. W. H. A. K. S. D. S., 2018. A proposal of the modification of Japanese society on thrombosis and hemostasis (JSTH) disseminated intravascular coagulation (DIC) diagnostic criteria for Sepsis- associated DIC. Clin. Appl. Thromb. Hemost, p. 24 (3); 439–445.
Hidayat, T. &. U. T., 2022. Asuhan Keperawatan Pada Ibu Masa Nifas Ny. R Dengan Hipertensi Di Prof Dr Margono Soekarjo Purwokerto. Jurnal Pengabdian Mandiri, pp. 1(7), 1307-1314.
Gomez-Tolub, R. R. A. K. E. B.-T. N. T. D. T. J. .. &. E. O., 2022. Placental abruption as a trigger of DIC in women with HELLP syndrome: a population-based study. The Journal of Maternal-Fetal & Neonatal Medicine, pp. 35(17), 3259-3269.
Lestari, L. I., 2019. Pengaruh Asupan Asam Folat Terhadap Kejadian Preeklamsi. Jurnal Ilmiah Kesehatan Sandi Husada, pp. 8(2), 85-89.