Potensi Akar Manis sebagai Pengobatan Infeksi Covid-19

Tasya Ellyana Putri

doi:10.37287/jppp.v3i3.539

Tasya Ellyana Putri Fakultas Kedokteran, Universitas Lampung

DOI: https://doi.org/10.37287/jppp.v3i3.539

Keywords: akar manis (glycyrrhiza glabra), covid-19, glycyrrhizin

Abstract

Infeksi COVID-19 merupakan penyakit yang disebabkan oleh Virus RNA Single Stranded yaitu Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV2). Tingkat penularan virus yang cepat dari manusia ke manusia menyebabkan pandemi. Tujuan dilakukannya literature review ini adalah untuk mengetahui potensi dari akar manis sebagai pengobatan infeksi COVID-19. Penulisan artikel ini menggunakan metode literature review. Artikel ini terbentuk atas informasi yang didapatkan dari 19 artikel dari jurnal internasional dan nasional yang didapatkan dari hasil literature searching dari database Pubmed, NCBI dan Google Scholar dengan kata kunci akar manis (Glycyrrhiza glabra); COVID-19; glycyrrhizin. Dari artikel yang didapatkan selanjutnya dianalisis dengan metode systemic literature review meliputi kegiatan pengumpulan, evaluasi, dan pengembangan penelitian dengan fokus tertentu. Hasil literature review ini didapatkan bahwa Akar manis (Glycyrrhiza glabra) memiliki kandungan glycyrrhizi yang berpotensi dapat mengobati infeksi COVID-19 dengan cara membatasi akses masuknya virus ke dalam sel sehingga memblokir terjadinya replikasi SARS-CoV2 dan mekanisme anti-inflamasinya melalui ekspresi ACE2.

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