Potensi Vitamin C untuk Mencegah Penyakit Paru Obstruktif Kronik

  • Devista Beki Srianuris Universitas Lampung
Keywords: pencegahan, PPOK, vitamin c

Abstract

Penyakit Paru Obstruktif Kronik (PPOK) adalah penyakit yang umum terjadi, dapat dicegah, dan dapat diobati yang ditandai dengan gejala pernapasan persisten dan keterbatasan aliran udara karena abnormalitas saluran udara atau alveolar yang biasanya disebabkan oleh paparan gas atau partikel berbahaya dan dipengaruhi oleh faktor penderita misalnya perkembangan paru yang abnormal. Sehingga diperlukan cara untuk mencegah PPOK, salah satunya adalah dengan pemantauan nutrisi berupa pemberian vitamin C. Tujuan ini bertujuan untuk mengetahui potensi vitamin C dalam pencegahan PPOK. Metode tinjauan literatur ini disusun menggunakan data sekunder berupa sumber yang diperoleh berdasarkan daftar pustaka yang tertera. Sumber pustaka yang digunakan yaitu berasal dari jurnal berupa artikel penelitian, guideline, ataupun buku elektronik seperti dari NCBI, Elsevier, WHO, dan jurnal kesehatan lainnya. Metode  analisis yang    digunakan adalah systematic literature  review dengan cara mengidentifikasi, mengkaji, mengevaluasi, serta mengembangkan secara  sistematis  penelitian  yang  sudah ada  dengan fokus  topik  tertentu  yang sesuai. Hasil analisis dari sumber pustaka menunjukan bahwa vitamin C memiliki potensi untuk menghasilkan efek positif pada tubuh pasien PPOK.

References

Alameda, C., Carlos Matiá, Á., & Casado, V. (2016). Predictors for mortality due to acute exacerbation of COPD in primary care: Protocol for the derivation of a clinical prediction rule. npj Primary Care Respiratory Medicine, 26(April), 2–4. https://doi.org/10.1038/npjpcrm.2016.70

Babu, D., Abraham, L., Raj, B. C., Majeed, H. P., & Banu, S. C. (2017). Sputum Bacteriology in Patients having Acute Exacerbation of Chronic Obstructive Pulmonary Disease in a Tertiary Care Hospital. International Journal of Medical Research & Health Sciences, 6(9), 1–5. Diambil dari www.ijmrhs.com

Berg, K., & Wright, J. L. (2016). The pathology of chronic obstructive pulmonary disease: Progress in the 20th and 21st centuries. Archives of Pathology and Laboratory Medicine, 140(12), 1423–1428. https://doi.org/10.5858/arpa.2015-0455-RS

Cantor, J. O., & Turino, G. M. (2019). COPD Pathogenesis: Finding the Common in the Complex. Chest, 155(2), 266–271. https://doi.org/10.1016/j.chest.2018.07.030

Collins, P. F., Yang, I. A., Chang, Y. C., & Vaughan, A. (2019). Nutritional support in chronic obstructive pulmonary disease (COPD): An evidence update. Journal of Thoracic Disease, 11(Suppl 17), S2230–S2237. https://doi.org/10.21037/jtd.2019.10.41

Devaki, S. J., & Raveendran, R. L. (2017). Vitamin C: Sources, Functions, Sensing and Analysis. Vitamin C, 3–20. https://doi.org/10.5772/intechopen.70162

Flattet, Y., Garin, N., Serratrice, J., Perrier, A., Stirnemann, J., & Carballo, S. (2017). Determining prognosis in acute exacerbation of COPD. International Journal of COPD, 12, 467–475. https://doi.org/10.2147/COPD.S122382

Global Initiative for Chronic Obstructive Lung Disease. (2020). Pocket guide to COPD diagnosis, management, and prevention: a guide for health care professionals, 2020 report. GOLD.

Grigorakos, L. (2018). The role of nutrition in patients with chronic obstructive pulmonary disease. Acta Scientific Nutritional Health, 2(4), 20–23.

Hartmann, S. E., Kissel, C. K., Szabo, L., Walker, B. L., Leigh, R., Anderson, T. J., & Poulin, M. J. (2015). Increased ventilatory response to carbon dioxide in COPD patients following Vitamin C administration. ERJ Open Research, 1(1), 1–9. https://doi.org/10.1183/23120541.00017-2015

Hong, J. Y., Lee, C. Y., Lee, M. G., & Kim, Y. S. (2018). Effects of dietary antioxidant vitamins on lung functions according to gender and smoking status in Korea: A population-based cross-sectional study. BMJ Open, 8(4), 1–9. https://doi.org/10.1136/bmjopen-2017-020656

Hsieh, M. J., Yang, T. M., & Tsai, Y. H. (2016). Nutritional supplementation in patients with chronic obstructive pulmonary disease. Journal of the Formosan Medical Association, 115(8), 595–601. https://doi.org/10.1016/j.jfma.2015.10.008

Khan, S., Fell, P., & James, P. (2014). Smoking-related chronic obstructive pulmonary disease ( COPD ). Diversity and Equality in Health and Care, 11, 267–271.

Koike, K., Ishigami, A., Sato, Y., Hirai, T., Yuan, Y., Kobayashi, E., … Seyama, K. (2014). Vitamin C prevents cigarette smoke-induced pulmonary emphysema in mice and provides pulmonary restoration. American Journal of Respiratory Cell and Molecular Biology, 50(2), 347–357. https://doi.org/10.1165/rcmb.2013-0121OC

Koo, H. K., Park, S. W., Park, J. W., Choi, H. S., Kim, T. H., Yoon, H. K., … Kim, D. K. (2018). Chronic cough as a novel phenotype of chronic obstructive pulmonary disease. International Journal of COPD, 13, 1793–1801. https://doi.org/10.2147/COPD.S153821

Lim, S., Lam, D. C. L., Muttalif, A. R., Yunus, F., Wongtim, S., Lan, L. T. T., … De Guia, T. (2015). Impact of chronic obstructive pulmonary disease (COPD) in the Asia-Pacific region: The EPIC Asia population-based survey. Asia Pacific Family Medicine, 14(1), 1–11. https://doi.org/10.1186/s12930-015-0020-9

Lõpez-Campos, J. L., Tan, W., & Soriano, J. B. (2016). Global burden of COPD. Respirology, 21(1), 14–23. https://doi.org/10.1111/resp.12660

Lykkesfeldt, J., & Tveden-Nyborg, P. (2019). The pharmacokinetics of vitamin C. Nutrients, 11(10). https://doi.org/10.3390/nu11102412

Martin, C., & Burgel, P. R. (2019). Do Cough and Sputum Production Predict COPD Exacerbations?: The Evidence Is Growing. Chest, 156(4), 641–642. https://doi.org/10.1016/j.chest.2019.06.023

Mosallanezhad, Z., Jalali, M., Eftekhari, M. H., & Ahmadi, A. (2019). The Effects of Vitamin C in Patients with Chronic Obstructive Pulmonary Disease : A Systematic Review of Clinical Trials. International Journal of Nutrition Sciences, 4(December), 170–174.

O’Donnell, D. E., Milne, K. M., James, M. D., de Torres, J. P., & Neder, J. A. (2020). Dyspnea in COPD: New Mechanistic Insights and Management Implications. Advances in Therapy, 37(1), 41–60. https://doi.org/10.1007/s12325-019-01128-9

Park, H. J., Byun, M. K., Kim, H. J., Kim, J. Y., Kim, Y. Il, Yoo, K. H., … Ahn, C. M. (2016). Dietary vitamin C intake protects against COPD: The Korea National Health and Nutrition Examination Survey in 2012. International Journal of COPD, 11(1), 2721–2728. https://doi.org/10.2147/COPD.S119448

Rabe, K. F., & Watz, H. (2017). Chronic obstructive pulmonary disease. The Lancet, 389(10082), 1931–1940. https://doi.org/10.1016/S0140-6736(17)31222-9

Salwen, M. J. (2017). Vitamins and Trace Elements. In Henry’s Clinical Diagnosis and Management by Laboratory Methods (Twenty Thi). https://doi.org/10.1016/B978-0-323-29568-0.00026-7

Schols, A. M., Ferreira, I. M., Franssen, F. M., Gosker, H. R., Janssens, W., Muscaritoli, M., … Singh, S. J. (2014). Nutritional assessment and therapy in COPD: A European respiratory society statement. European Respiratory Journal, 44(6), 1504–1520. https://doi.org/10.1183/09031936.00070914

Shaykhiev, R., & Crystal, R. G. (2014). Early events in the pathogenesis of chronic obstructive pulmonary disease: Smoking-induced reprogramming of airway epithelial basal progenitor cells. Annals of the American Thoracic Society, 11(December), S252–S258. https://doi.org/10.1513/AnnalsATS.201402-049AW

Wallig, M. A., & Keenan, K. P. (2013). Nutritional Toxicologic Pathology. In Haschek and Rousseaux’s Handbook of Toxicologic Pathology (Third Edit). https://doi.org/10.1016/B978-0-12-415759-0.00036-4

Wen, H., Xie, C., Wang, L., Wang, F., Wang, Y., Liu, X., & Yu, C. (2019). Difference in long-term trends in COPD mortality between China and the U.S., 1992–2017: An age–period–cohort analysis. International Journal of Environmental Research and Public Health, 16(9). https://doi.org/10.3390/ijerph16091529

Published
2020-12-05
How to Cite
Srianuris, D. (2020). Potensi Vitamin C untuk Mencegah Penyakit Paru Obstruktif Kronik. Jurnal Penelitian Perawat Profesional, 3(1), 31-40. https://doi.org/10.37287/jppp.v3i1.243