Lichen Amyloidosis Resembles A Picture Chronic Lichen Simplex in A Woman with Hyperpigmented Skin Lesions Area Lower Legs

Jilly Selena Pradipta

doi:10.37287/ijghr.v6iS6.5433

Jilly Selena Pradipta Apotek Anugerah Gatot Subroto Denpasar

DOI: https://doi.org/10.37287/ijghr.v6iS6.5433

Keywords: histopathological examination, hyperpigmentation lesions, lichen amyloidosis, lichen simplex chronicus, skin lesions

Abstract

Lichen Amyloidosis (LA) and Lichen Simplex Chronicus (LSC) are two skin conditions that are often confused in clinical diagnosis because of their similar clinical manifestations. Objective: This study aims to determine the picture of Lichen Amyloidosis Resembling Lichen Simplex Chronicus in Women with Hyperpigmented Skin Lesions in the Lower Leg Area. This study used a qualitative method with a case study approach on participants who met the inclusion and exclusion criteria in women with hyperpigmented skin lesions in the lower leg area. The population and samples used were patients who met the inclusion and exclusion criteria as many as 3 people. patients were interviewed, observed and given medical treatment then evaluated for changes that occurred. The results of this study found a case of a 37-year-old woman with hyperpigmented skin lesions on both lower legs, diagnosed as LSC. Further examination showed results in accordance with LA. The main symptoms experienced by the patient were severe itching that interfered with daily activities, especially when the patient was emotional or stressed. The patient was treated using a combination of dermatotherapy and psychotherapy to reduce itching and prevent recurrence. Diagnostic challenges are often encountered in the management of patients with complex skin conditions, as is the importance of accurate histopathology in establishing a correct diagnosis.

References

Carolin, A., & Saraswati, PDA (2023). Lichen Amyloidosis - Diagnosis and Therapy. Mirror of the World of Medicine, 50(6), 306–309. https://doi.org/10.55175/cdk.v50i6.917

Chu, H., Shin, JU, Lee, J., Park, CO, & Lee, K. H. (2017). Successful treatment of lichen amyloidosis accompanied by atopic dermatitis by fractional CO2 laser. Journal of Cosmetic and Laser Therapy, 19(6), 345–346. https://doi.org/10.1080/14764172.2017.1326612

Clement, C. G., & Truong, L. D. (2014). An evaluation of Congo red fluorescence for the diagnosis of amyloidosis. Human Pathology, 45(8), 1766–1772. https://doi.org/10.1016/j.humpath.2014.04.016

Gorevic, P., & Phelps, R. (2019). Amyloidosis. In S. Kang, M. Amagai, A.L. Bruckner, A.H. Enk, D.J. Margolis, A.J. McMichael, & J.S. Orringer (Eds.), Fitzpatrick's Dermatology in General Medicine (9th ed., pp. 2258–70). McGraw Hill Education.

Hamie, L., Haddad, I., Nasser, N., Kurban, M., & Abbas, O. (2021). Primary Localized Cutaneous Amyloidosis of Keratinocyte Origin: An Update with Emphasis on Atypical Clinical Variants. American Journal of Clinical Dermatology, 22(5), 667–680. https://doi.org/10.1007/s40257-021-00620-9

Hasibah, UH (2023). Lichen amyloidosis is treated with topical combination therapy and narrowband ultraviolet B phototherapy. Journal of General - Procedural Dermatology & Venereology Indonesia, 7(2). https://doi.org/10.7454/jdvi.v7i2.1153

Juarez, M.C., & Kwatra, S.G. (2021). A systematic review of evidence based treatments for lichen simplex chronicus. Journal of Dermatological Treatment, 32(7), 684–692. https://doi.org/10.1080/09546634.2019.1708856

Kandhari, R., Ramesh, V., & Singh, A. (2013). A generalized, non-pruritic variant of lichen amyloidosis: A case report and a brief review. Indian Journal of Dermatology, 58(4), 328.

Kubanov, AA, Karamova, AE, Chikin, VV, Znamenskaya, LF, Kondrashova, VV, & Nefedova, MA (2018). Cutaneous lichen amyloidosis within scratched areas. Russian Open Medical Journal, 7(2), 2–5. https://doi.org/10.15275/rusomj.2018.0205

Ladizinski, B., & Lee, K. C. (2014). Lichen amyloidosis. Canadian Medical Association Journal, 186(7), 532–532. https://doi.org/10.1503/cmaj.130698

Maouni, S., Mezni, L., Abdelmoutalib, A., Znati, K., Meziane, M., Ismaili, N., Senouci, K., & Benzekri, L. (2020). Generalized lichen amyloidosis. Our Dermatology Online, 11(4), 436–437. https://doi.org/10.7241/ourd.20204.30

Milewska, J., Małachowska, U., Czuwara, J., Rudnicka, L., & Olszewska, M. (2023). Lichen amyloidosis. Przeglad Dermatologiczny, 110(1), 37–42. https://doi.org/10.5114/dr.2023.127656

Muramatsu, T., Honoki, K., & Shirai, T. (1995). Localized cutaneous amyloidosis simulating lichen simplex chronicus. Journal of Dermatology, 22(10), 759–763. https://doi.org/10.1111/j.1346-8138.1995.tb03916.x

Oh, S. M., Ahn, H. J., & Shin, M. K. (2023). Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study. Annals of Dermatology, 35(6), 432–438. https://doi.org/10.5021/ad.23.006

Ouiam, E. A. (2018). Clinical and Dermoscopic Features of Lichen Amyloidosis : A Case Report. Theranostics of Respiratory & Skin Diseases, 1(2), 57–58. https://doi.org/10.32474/trsd.2018.01.000109

Panicker, V.V., Jagadeesan, S., Anjaneyan, G., S., L., Eapen, M., V., S., & Thomas, J. (2017). A clinicopathological study of primary localized cutaneous amyloidosis. International Journal of Research in Dermatology, 3(4), 470. https://doi.org/10.18203/issn.2455-4529.intjresdermatol20174649

Rousseau, M. A., Valek, S. A., & Rashid, R. M. (2023). A Case Report of Generalized Non-pruritic Lichen Amyloidosis. Cureus, 15(6), 6–8. https://doi.org/10.7759/cureus.39817

Shimoda, Y., Sato, Y., Hayashida, Y., Yamazaki, Y., Mizukawa, Y., Nakajima, K., Shiohara, T., & Aoyama, Y. (2017). Lichen amyloidosus as a sweat gland/duct-related disorder: resolution associated with restoration of sweating disturbance. British Journal of Dermatology, 176(5), 1308–1315. https://doi.org/10.1111/bjd.15060

Smogorzewski, J.M., Rodriguez, L., & LorraineYoung. (2019). Symmetric lichen amyloidosis: An atypical location on the bilateral extensor surfaces of the arms. Cutis, 103(4), E9–E10.

Solimani, F., Dilling, A., Ghoreschi, F.C., Nast, A., Ghoreschi, K., & Meier, K. (2023). Upadacitinib for treatment-resistant lichen amyloidosis. Journal of the European Academy of Dermatology and Venereology, 37(5), e633–e635. https://doi.org/10.1111/jdv.18756

Sufiawati, I., Megawati, A., Al Farisyi, M., & Putra, INGJ (2022). A Case Series of Psychological Stress Evaluation as a Risk Factor for Oral Lichen Planus. Case Reports in Dentistry, 2022, 11–13. https://doi.org/10.1155/2022/1915122

Tiengo, C., Deluca, J., Belloni-Fortina, A., Salmaso, R., Galifi, F., & Alaibac, M. (2012). Occurrence of squamous cell carcinoma in an area of lichen simplex chronicus: Case report and pathogenetic hypothesis. Journal of Cutaneous Medicine and Surgery, 16(5), 350–352. https://doi.org/10.2310/7750.2011.11048

Weidner, T., Illing, T., & Elsner, P. (2017). Primary Localized Cutaneous Amyloidosis: A Systematic Treatment Review. American Journal of Clinical Dermatology, 18(5), 629–642. https://doi.org/10.1007/s40257-017-0278-9